Significance of Positive control
Positive control refers to samples or treatment groups in experiments that are known to yield a positive result, serving as a benchmark for comparison against test samples. They validate the experimental method and ensure that the assay can detect the intended effects. Positive controls can include known substances, such as retinoic acid, Cyclophosphamide, or standard drugs like amoxicillin and ciprofloxacin, used to assess the effectiveness of new treatments or substances in various scientific studies.
Synonyms: Reference control, Standard control, Reference point, Standard, Calibration, Comparison, Baseline
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Positive control in scientific sources
Positive control is essential in experiments as it serves as a benchmark, typically involving known substances like insulin, glibenclamide, or acetic acid, enabling comparison of treatment effectiveness against established standards or controls.
From: The Malaysian Journal of Medical Sciences
(1) These are controls included in each assay, which are used with negative controls, as the text explains.[1] (2) These are specimens from confirmed positive cases, included with each batch of slides to ensure the accuracy and reliability of the in situ hybridization process.[2] (3) These are substances, such as chloramphenicol and nystatin, used in the antimicrobial activity tests to ensure that the assays are working correctly.[3] (4) The phage clones generated with the dengue anti-complex monoclonal antibody H3/6 were used as a positive control.[4] (5) A positive control is a substance, such as 1% Triton X-100, that is known to produce a specific effect, in this case, 100% haemolysis, and is used as a comparison.[5]