Significance of Phorbol esters
Phorbol esters are toxic constituents derived from the seeds of Croton tiglium, which contribute to the seeds' purgative effects. Additionally, these chemical compounds serve as signal transducers in biological processes and have been linked to tumor promotion. Thus, Phorbol esters play a dual role in both traditional medicine and modern biochemical research, highlighting their significance in understanding both toxicity and cancer biology.
Synonyms: Tumor promoters
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The concept of Phorbol esters in scientific sources
Phorbol esters, derived from Croton tiglium seeds, are toxic constituents responsible for their purgative effects and act as signal transducers that can promote tumor growth, highlighting their dual role in both toxicity and carcinogenicity.
From: Ancient Science of Life
(1) Toxic constituents found in Croton tiglium seeds that contribute to their purgative action.[1]
From: World Journal of Pharmaceutical Research
(1) Chemical compounds that function as signal transducers and are known to promote tumors.[2]