Significance of Multi Drug Resistance
Multi-drug resistance (MDR) is a critical phenomenon where bacteria and cancer cells develop resistance to multiple antibiotics or chemotherapeutic agents, respectively. This resistance complicates treatment options and poses significant challenges in managing infections and cancer effectively. For bacteria, it leads to more complicated infections and health threats. In cancer treatment, MDR limits the efficacy of chemotherapy and necessitates novel approaches to combat this growing global health issue, ultimately making it increasingly difficult for healthcare providers to ensure successful treatment outcomes.
Synonyms: Antimicrobial resistance, Drug resistance, Multidrug resistance, Antibiotic resistance, Drug tolerance
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The concept of Multi Drug Resistance in scientific sources
Multi Drug Resistance indicates pathogens' ability to withstand various antibiotics, particularly seen in Mycobacterium leprae, complicating treatment and often arising from prolonged antibiotic use, presenting significant challenges in managing infections effectively.
From: The Malaysian Journal of Medical Sciences
(1) This is the ability of bacteria to resist multiple antibiotics, which complicates treatment and increases the risk of treatment failure.[1] (2) Multi-drug resistance (MDR) is classified as acquired non-susceptibility to at least one agent in three or more antimicrobial categories among VTEC isolates.[2] (3) The ability of certain bacteria to withstand the effects of multiple types of medications, which presents a challenge in treating infections and is explored using various systems biology approaches.[3] (4) This is the emergence of bacterial resistance to multiple antibiotics, greatly exacerbating concerns of scientists and medical professionals in Malaysia.[4] (5) A characteristic of certain bacterial strains, including ESBL strains, that allows them to resist multiple antibiotics, complicating treatment options.[5]