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Significance of Lower dose

Lower dose refers to the findings from various studies indicating that smaller quantities of herbal extracts and medications can result in less severe toxicological risks and fewer side effects. In particular, it encompasses instances such as the administration of 50 mg/kg of Vedanasthapana gana for analgesic effects and 90 mg/kg doses for comparative analyses. Additionally, smaller doses like 15 mg of Syzygium aromaticum improved sperm motility without reducing libido, showcasing the potential benefits of lower dosages in achieving effective therapeutic outcomes.

Synonyms: Reduced dose, Minimal dose, Lesser amount

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

The concept of Lower dose in scientific sources

Science Books

The keyphrase "Lower dose" pertains to administering 50 mg/kg of Vedanasthapana gana in a study to assess analgesic effects, contrasting with a higher dose of 90 mg/kg evaluated for comparative analysis.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) Refers to the findings suggesting that lower doses of the extracts are likely to produce less severe toxicological risk.[1] (2) Refers to administering a lower concentration of Murraya koenigii leaf extract (100 mg/kg) which lacked significant effects.[2] (3) Refers to smaller concentrations of AgNPs that reduced cytotoxicity in cell lines.[3] (4) A reduced amount of herbal preparation necessary when synergistic effects are present, potentially minimizing side effects while achieving desired pharmacological actions.[4] (5) The lower dose level of 2000mg/kg body weight administered to one group of rats, which showed no significant adverse effects.[5]

From: AYU (Journal of Research in Ayurveda)

(1) The smaller amount of medication (90 mg/kg) administered in the study to evaluate its effects in comparison to the higher dose.[6]

From: International Ayurvedic Medical Journal

(1) In the context of the study, refers to the administration of 50 mg/kg of Vedanasthapana gana to evaluate its analgesic effects.[7]

From: Journal of Ayurveda and Integrative Medicine

(1) Specifically indicated as 15 mg of Syzygium aromaticum, which enhanced sperm motility and secretory activity without diminishing libido.[8]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.