Significance of Hydrogen bonding
Hydrogen bonding is an essential type of intermolecular force characterized by the weak attraction between a hydrogen atom covalently bonded to a highly electronegative atom and another electronegative atom. This interaction plays a crucial role in various biological and chemical processes, including the stabilization of molecular structures, protein-ligand interactions, and solute-solvent dynamics. By influencing the stability and properties of compounds, hydrogen bonding is significant in fields such as drug development and material science, impacting drug efficacy and solubility.
Synonyms: Electrostatic interaction, Van der waals force
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The concept of Hydrogen bonding in scientific sources
Hydrogen bonding is a weak attractive interaction between hydrogen and electronegative atoms, crucial for compound interactions, including nevirapine with BSA and stability in molecules like allicin found in garlic extracts.
From: World Journal of Pharmaceutical Research
(1) Chemical interactions within PVA molecules that affect the material's properties when modified with glycerin.[1] (2) A type of non-covalent interaction that significantly contributes to the stability of molecular complexes.[2] (3) A type of attractive interaction between a hydrogen atom bonded to an electronegative atom and another electronegative atom.[3] (4) A type of attractive interaction between a hydrogen atom that is bonded to a highly electronegative atom and another electronegative atom.[4] (5) The intermolecular attraction that plays a crucial role in the stability and properties of the synthesized compounds.[5]
From: AYU (Journal of Research in Ayurveda)
(1) A type of chemical bond that is involved in stabilizing molecules such as allicin in garlic extracts.[6]