Significance of Half maximal inhibitory concentration
Half maximal inhibitory concentration, commonly abbreviated as IC50, refers to the concentration of a substance needed to inhibit a biological process by half. It serves as a crucial measurement for determining the effectiveness of a drug or compound in inhibiting specific biological functions or pathogen growth. This measure indicates the concentration that produces 50% of the maximum inhibitory effect, making it essential for evaluating the efficacy of various substances in biological and biochemical contexts.
Synonyms: Ic50, Median inhibitory concentration
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The concept of Half maximal inhibitory concentration in scientific sources
Half maximal inhibitory concentration (IC50) measures the concentration at which a compound inhibits 50% of a biological function, critical for assessing the efficacy of substances in pharmacology and biochemistry.
From: The Malaysian Journal of Medical Sciences
(1) A measure of a drug's potency shown by the concentration required to inhibit a biological process by half, relevant in evaluating compounds like ellagic acid.[1] (2) A measure used to determine the effectiveness of a drug in inhibiting a specific biological function or pathogen growth.[2]