Significance of Guillain-Barre syndrome
Guillain-Barre syndrome (GBS) is a rare neurological disorder characterized by the immune system attacking the peripheral nervous system, resulting in rapid-onset muscle weakness and paralysis. It often follows infections, including Campylobacter jejuni and Zika virus, leading to acute, potentially severe polyradiculopathy. Symptoms include symmetrical weakness and areflexia, and it can evolve rapidly, sometimes requiring immediate medical attention. GBS may have life-threatening consequences and is marked by high protein levels in cerebrospinal fluid.
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Guillain-Barre syndrome in scientific sources
Guillain-Barre syndrome is a postinfectious autoimmune disorder affecting peripheral nerves, leading to rapid progressive weakness and sensory/autonomic issues, often following infections. It features demyelination and may resemble other conditions while exhibiting unique respiratory symptoms.
From: The Malaysian Journal of Medical Sciences
(1) An autoimmune disorder where the immune system attacks the nerves, potentially leading to paralysis and neurologic symptoms.[1] (2) A rare neurological disorder that can occur after a Zika virus infection, characterized by the immune system destroying the protective sheath that covers peripheral nerves.[2]