Significance of Glycolytic enzyme
Glycolytic enzymes are crucial for the glycolysis process, which breaks down glucose to generate energy. These enzymes can be affected by liver toxicity and changes in diabetic conditions, as demonstrated in studies involving alloxan-induced diabetic rats where elevated levels of glycogen phosphorylase and glucose-6-phosphatase were noted. Additionally, the activity of these enzymes is influenced by certain treatments and was found to be androgen-dependent, highlighting their role in metabolic regulation.
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The concept of Glycolytic enzyme in scientific sources
Glycolytic enzymes facilitate glycolysis, breaking down glucose for energy. Elevated levels were found in diabetic rats, with activity potentially altered by treatments and shown to be androgen-dependent in studies.
From: The Malaysian Journal of Medical Sciences
(1) Glycolytic enzymes are upregulated in CAFs when HIF-1α reprograms the metabolic state of CAFs into glycolysis, increasing glucose uptake and inhibiting OXPHOS.[1]