Significance of Genotoxicity
Genotoxicity refers to the potential of substances to cause damage to genetic information within a cell, which can lead to mutations and increase the risk of cancer. This harmful effect can stem from various chemical agents and pollutants, including pesticides and certain natural compounds. Genotoxicity is assessed through various studies to understand the implications of exposure to these substances, including their ability to interact with DNA and contribute to genetic disorders. The investigation of protective agents against genotoxicity is also significant.
Synonyms: Dna damage, Mutagenicity, Carcinogenicity, Genetic toxicity, Chromosome damage
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Genotoxicity in scientific sources
Genotoxicity pertains to the capacity of compounds to damage DNA and genetic material, which can result in mutations. It is assessed through experimental methods, including studies involving Acmella oleracea extracts, highlighting its significance in evaluating chemical safety.
From: The Malaysian Journal of Medical Sciences
(1) The property of certain substances, like safranal in high doses, to cause damage to genetic information within a cell.[1]