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Significance of Friability test

The Friability test is a quality control procedure used to determine the mechanical strength and durability of tablets by assessing their tendency to break or crumble under mechanical stress. The test measures the percentage weight loss of tablets subjected to mechanical abrasion during handling, packaging, and transportation. A proper Friability test ensures that tablets maintain their structural integrity and can withstand environmental factors without significant loss of material. An acceptable friability percentage is typically less than 1%.

Synonyms: Tablet hardness test

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

The concept of Friability test in scientific sources

Science Books

The Friability test measures the mechanical strength and physical stability of tablets, particularly assessing how resistant they are to breaking or crumbling under stress, which is crucial for quality control in products like Sanjivani Vati tablets.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) A test assessing the durability of tablets, measuring weight loss when subjected to friction and impact.[1] (2) A test that measures the durability of tablets by evaluating the weight loss after subjecting them to abrasion.[2] (3) The friability test measures a tablet's ability to withstand abrasion during packaging, handling, and shipping, indicating its robustness.[3] (4) A method used to assess the toughness of tablets by weighing them before and after undergoing a specific rotation in the Roche friabilator.[4] (5) Friability test measures a tablet's ability to withstand mechanical stress without breaking, typically assessed through a specific measurement process.[5]

From: International Ayurvedic Medical Journal

(1) A quality control test that evaluates the tendency of Sanjivani Vati tablets to break or lose powder due to mechanical shock.[6] (2) A measure of the mechanical strength of tablets, indicating how resistant they are to breaking or crumbling under stress.[7]

From: AYU (Journal of Research in Ayurveda)

(1) A method to assess the tendency of a tablet to crumble under pressure or during handling, indicating its physical stability.[8]

From: Journal of Ayurveda and Integrative Medicine

(1) The friability test measures the tendency of the pills to crumble under pressure, evaluating the mechanical strength of the pills.[9]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.