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Significance of Epidermis

The epidermis is defined as the outermost layer of skin, serving as a crucial protective barrier that retains moisture, regulates permeability, and provides defense against environmental factors. It is composed primarily of stratified squamous epithelium and includes various cell types, such as keratinocytes and melanocytes. This layer contains no blood vessels and is vital for preventing water loss while also playing a role in drug permeation and absorption. Conditions like eczema can manifest within the epidermis, highlighting its importance in skin health.

Synonyms: Skin, Hide, Dermis, Outer layer, Integument, Hide.

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The concept of Epidermis in scientific sources