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Significance of End-stage renal failure

End-stage renal failure is the final stage of chronic kidney disease characterized by the kidneys' inability to function adequately, necessitating treatments such as dialysis or transplantation. This terminal phase results from various conditions, including recurrent urinary tract infections and untreated urolithiasis, leading to a significant loss of renal function. Patients suffering from end-stage renal failure face serious health complications and rely on renal replacement therapy to sustain their lives, as the kidneys can no longer effectively filter waste and fluids from the blood.

Synonyms: End-stage renal disease, Chronic kidney failure, Kidney failure, Kidney disease, Renal insufficiency, Chronic kidney disease, Renal dysfunction

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The concept of End-stage renal failure in scientific sources