Significance of Dose-dependent
Dose-dependent refers to the relationship where the effects of a substance or treatment increase or decrease in proportion to the amount administered. This concept is crucial in understanding how therapeutic agents like Kshara, lectins, and various extracts influence biological activities such as analgesic, anti-inflammatory, and antioxidant effects. In numerous studies, varying dosages have been shown to correlate with differing levels of impact, highlighting the importance of dosage in achieving desired therapeutic outcomes and understanding substance safety and efficacy.
Synonyms: Dosage-dependent, Concentration-dependent
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Dose-dependent in scientific sources
Dose-dependent signifies that the effectiveness of a treatment correlates with the administered amount, as seen in S. jambos extract, reflecting how responses to drugs or substances change in relation to dosage increases.
From: The Malaysian Journal of Medical Sciences
(1) A relationship where the effect of a substance varies with the amount administered, which was observed in the extracts' inhibitory effects.[1] (2) This means that the effect of the treatment varies based on the amount given, suggesting that the intensity of the effect on the mother's weight depended on the dosage of the extract.[2] (3) A relationship where the risk of adverse outcomes increases with the number of packed red blood cell transfusions, which was observed in the study for several post-operative adverse events.[3] (4) This term refers to the relationship between the amount of a substance and its effect, and the study tested this relationship for the honey's inhibition activity.[4] (5) This describes how the TFC content of the extracts changes, as well as the cytotoxicity observed in the study.[5]