Significance of Chronic renal failure
Chronic renal failure (CRF) is a progressive and irreversible condition characterized by a gradual loss of kidney function, often resulting from untreated urinary tract infections or diabetic nephropathy. As kidney function deteriorates, it leads to diverse complications such as the accumulation of waste products, hypertension, and anemia. CRF can necessitate treatments like dialysis or transplantation and is a significant health issue linked to lifestyle factors and increased morbidity and mortality rates. Early diagnosis and management are crucial to slowing progression.
Synonyms: Chronic kidney disease, Chronic renal insufficiency, Chronic kidney failure, End-stage renal disease, Ckd, Renal dysfunction, Nephropathy
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The concept of Chronic renal failure in scientific sources
Chronic renal failure is characterized by a long-term decline in kidney function due to factors like drug toxicity and lifestyle changes, leading to symptoms such as edema, hypertension, and increased serum creatinine, prevalent in India.
From: The Malaysian Journal of Medical Sciences
(1) This is a gradual loss of kidney function over time, which can eventually lead to end-stage renal disease.[1] (2) This is a condition where the kidneys are not functioning properly, and it was once thought to be linked to elevated levels of a specific biomarker.[2]