Significance of Chromosomal abnormalities
Chromosomal abnormalities refer to genetic disorders caused by changes in the number or structure of chromosomes. These abnormalities can lead to various health issues, including congenital disorders, infertility, pregnancy complications, and an increased risk of certain cancers. They may result from environmental factors, maternal age, or genetic predispositions and can significantly impact development and overall health. Understanding these abnormalities is crucial for diagnosis, treatment, and prevention of associated conditions like miscarriages and syndromic diseases.
Synonyms: Chromosomal anomalies, Genetic abnormalities, Chromosomal variations, Genetic anomalies
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The concept of Chromosomal abnormalities in scientific sources
Chromosomal abnormalities are genetic defects resulting in complications like pregnancy loss and developmental issues. They include variations such as monosomy and trisomy, stemming from genetic factors and environmental influences like Bija dusti.
From: The Malaysian Journal of Medical Sciences
(1) These are gross changes in chromosomes that may cause some isolated cases of schizophrenia, highlighting a potential genetic cause of the disorder.[1] (2) These are changes in the structure or number of chromosomes that are associated with various diseases, including cancer.[2] (3) Irregularities in chromosome structure or number, such as deletions, duplications, or translocations, that can have significant implications for the progression and treatment of acute myeloid leukaemia.[3] (4) Irregularities in chromosome structure or number that can impact genetic stability and lead to various health issues.[4] (5) Chromosomal abnormalities refer to structural or numerical alterations in chromosomes that can lead to various diseases, including genetic conditions and increased risk for stroke.[5]