Significance of Chromatin remodeling
Chromatin remodeling is a crucial biological process that alters the structure of chromatin, ultimately influencing gene expression by modifying DNA accessibility for transcription. This involves reversible post-translational modifications of histone tails, which play a significant role in regulating how genes are accessed for transcription. Through these structural changes, chromatin remodeling effectively governs the interactions between DNA and transcription machinery, underscoring its importance in cellular function and gene regulation.
Synonyms: Chromatin restructuring
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The concept of Chromatin remodeling in scientific sources
Chromatin remodeling is essential for regulating gene expression by altering chromatin structure, thereby influencing DNA accessibility. This process facilitates necessary genetic transactions, ensuring proper cellular function and response to environmental signals.
From: World Journal of Pharmaceutical Research
(1) Changes to the structure of chromatin that can impact gene expression, relevant in the context of inflammation regulation.[1] (2) The process by which the structure of chromatin is altered to change DNA accessibility for transcription.[2] (3) Involves reversible post-translational modification of amino acids in the histone tails.[3] (4) A process that modifies the structure of chromatin, affecting the accessibility of DNA for transcription and thus influencing gene expression.[4] (5) Chromatin remodeling is the process by which the structure of chromatin is altered to regulate gene expression and access to the DNA.[5]