Significance of Beta-lactamase enzyme
Beta-lactamase enzyme is an important component in antibiotic resistance, as it blocks the activity of beta-lactam antibiotics. This enzyme can be encoded by the blaCTX-M gene and is responsible for hydrolyzing specific antibiotics in certain bacteria, thereby promoting their resistance. Understanding the function and implications of beta-lactamase is crucial in addressing the challenges posed by antibiotic-resistant infections.
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The concept of Beta-lactamase enzyme in scientific sources
Beta-lactamase enzyme, encoded by the blaCTX-M gene, contributes to antibiotic resistance in bacteria by hydrolyzing beta-lactam antibiotics, thus blocking their efficacy and highlighting a crucial aspect of bacterial defense mechanisms.
From: The Malaysian Journal of Medical Sciences
(1) This phrase refers to an enzyme that can block the activity of the beta-lactamase, which is a key component of the antibiotic resistance mechanism.[1] (2) This is the enzyme that can be coded by the blaCTX-M gene, and can cause hydrolysis in certain bacteria, contributing to resistance.[2]