Significance of Acute and sub-acute toxicity
Acute and sub-acute toxicity refer to the assessment of harmful effects caused by the administration of substances, such as Thalaga Kuligai, on experimental rats. Acute toxicity involves evaluating the immediate toxic effects observed shortly after exposure, while sub-acute toxicity addresses the harmful effects that arise from extended exposure over a moderate timeframe. Both types of toxicity are critical for understanding the safety and potential risks associated with various substances.
Synonyms: Acute toxicity, Sub-acute toxicity, Short-term toxicity, Chronic toxicity, Prolonged toxicity
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The concept of Acute and sub-acute toxicity in scientific sources
Acute and sub-acute toxicity assess a substance's harmful effects over short and moderate exposure durations. Acute toxicity manifests shortly after exposure, while sub-acute toxicity reflects effects after longer exposure periods.
From: World Journal of Pharmaceutical Research
(1) Studies focusing on the immediate and short-term toxic effects of whole plant aqueous extract from Crataegus aronia in Wistar rats.[1] (2) The degree of harmful effects caused by a substance following short-term (acute) or moderately prolonged (sub-acute) exposure, particularly noted in animal models.[2] (3) The evaluation of both immediate (acute) and prolonged (sub-acute) harmful effects resulting from the administration of Thalaga Kuligai on experimental rats.[3] (4) Refers to the evaluation of the toxic effects of a substance within short and moderately extended periods, respectively.[4]
From: AYU (Journal of Research in Ayurveda)
(1) Terms referring to the toxic effects observed shortly after (acute) and after a longer period of exposure (sub-acute) to a substance.[5]