Significance of Acetylcholinesterase inhibitor
Acetylcholinesterase inhibitor refers to medications designed to inhibit the acetylcholinesterase enzyme, which breaks down acetylcholine, thereby increasing its levels in the brain. This increase may alleviate symptoms associated with Alzheimer's disease and enhance cognitive functions. These inhibitors, including drugs such as Donepezil, Rivastigmine, and Galantamine, are instrumental in improving cholinergic transmission and potentially benefiting patients with various neurological conditions, including cognitive impairments related to diabetes.
Synonyms: Cholinesterase inhibitor
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The concept of Acetylcholinesterase inhibitor in scientific sources
Acetylcholinesterase inhibitors are compounds that block the enzyme acetylcholinesterase, potentially aiding in the treatment of various neurological conditions by enhancing acetylcholine levels in the brain.
From: The Malaysian Journal of Medical Sciences
(1) These are the current medical treatments for Alzheimer’s disease, which aim to increase the availability of acetylcholine, and the plant extract has been shown to inhibit these enzymes.[1] (2) These are substances that reduce the activity of acetylcholinesterase, an enzyme that breaks down acetylcholine, which is essential for memory and learning.[2] (3) Compounds that enhance cognitive functions in rats following experiences of hypobaric hypoxia.[3]