Pharmacognostic, Phytochemical, and Antimicrobial Study of Vidangadi Churna
Journal name: Ayushdhara
Original article title: Pharmacognostic, Phytochemical and Antimicrobial Study of Vidangadi Churna - An Experimental Study
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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Chhaju Ram Yadav
Professor and Head, Dept of Kriya Sharir, National Institute of Ayurveda, Deemed University, Jaipur, Rajasthan, India.
Chudasama Hardik Y
PhD Scholar, Dept of Kriya Sharir, National Institute of Ayurveda, Deemed University, Jaipur, Rajasthan, India.
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: Pharmacognostic, Phytochemical and Antimicrobial Study of Vidangadi Churna - An Experimental Study
Year: 2024 | Doi: 10.47070/ayushdhara.v11i3.1586
Copyright (license): CC BY-NC-SA 4.0
Summary of article contents:
Introduction
Herbal medicines have been used for centuries and are increasingly recognized for their therapeutic potential with minimal side effects when administered correctly. However, the lack of standardization and quality control data poses challenges for their reliable use. This highlights the necessity to validate herbal formulations like Vidangadi Churna using advanced methodologies. Vidangadi Churna, composed of five constituents including Embelia ribes and Triphala, is traditionally used in Ayurvedic practice for various health conditions. This study aimed to analyze the physio-chemical characteristics and antimicrobial efficacy of Vidangadi Churna against specific pathogens.
Phytochemical Analysis of Vidangadi Churna
The phytochemical examination of Vidangadi Churna revealed the presence of various active constituents known for their antimicrobial properties. The study identified phenolic compounds, tannins, alkaloids, and amino acids using standardized testing methods, including thin layer chromatography. This analysis supports the traditional claims of the formulation's therapeutic benefits and its role in addressing skin-related ailments. Furthermore, the different responses observed under ultraviolet light with various reagents indicate the potential complexity and richness of the phytochemistry present in Vidangadi Churna.
Antimicrobial Activity Assessment
The antimicrobial study conducted revealed the potency of Vidangadi Churna against common infective pathogens such as Klebsiella aerogenes, Escherichia coli, and Staphylococcus aureus. Using the Agar well diffusion method, the study assessed the zone of inhibition produced by different concentrations (5%, 10%, and 15%) of the preparation. Results showed that while lower concentrations were less effective, the 15% concentration demonstrated significant antimicrobial activity, particularly against the aforementioned microbial strains. This finding supports the traditional use of Vidangadi Churna in treating infections and reinforces the importance of using adequately high concentrations to achieve therapeutic effects.
Conclusion
The study concludes that the standardization and quality control of herbal formulations like Vidangadi Churna are essential to ensure high efficacy and safety. Through thorough organoleptic, physio-chemical, and phytochemical analyses, alongside rigorous antimicrobial testing, Vidangadi Churna demonstrates significant antimicrobial properties against certain pathogens. This research underscores the validity of Ayurvedic practices while encouraging further investigations into higher concentrations for potential effectiveness against other resistant strains, such as Pseudomonas aeruginosa. Overall, such studies are crucial in promoting the responsible use of genuine herbal formulations for the benefit of public health.
FAQ section (important questions/answers):
What is the purpose of the study on Vidangadi Churna?
The study aims to analyze the physio-chemical characters and antimicrobial potency of Vidangadi Churna against specific pathogens, including Klebsiella aerogenes, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.
What methods were used to test the antimicrobial activity?
The antimicrobial activity was tested using the Agar well diffusion method. Various concentrations of Vidangadi Churna (5%, 10%, and 15%) were prepared in DMSO, and the zone of inhibition was measured after incubating the plates with bacterial cultures.
What were the main findings of the pharmacognostic and antimicrobial study?
The study found that Vidangadi Churna contains various phytochemical constituents with antimicrobial properties. It demonstrated significant antimicrobial activity, particularly at a 15% concentration against the tested pathogens, suggesting its potential as an antimicrobial agent.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Pharmacognostic, Phytochemical, and Antimicrobial Study of Vidangadi Churna�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
The term 'drug' refers to a substance used for medical treatment, particularly as a medication to cure or prevent disease. In the context of this text, Vidangadi Churna is an Ayurvedic drug studied for its pharmacognostic, phytochemical, and antimicrobial properties to validate its use against various microbial infections.
2) Phytochemical:
Phytochemicals are naturally occurring chemical compounds found in plants. The study on Vidangadi Churna includes phytochemical screening to identify the presence of beneficial compounds like phenolic compounds, tannins, and alkaloids, which contribute to its antimicrobial activity.
3) Aureus:
This refers to the bacterium Staphylococcus aureus, a common cause of infections. The research on Vidangadi Churna demonstrated its antimicrobial effectiveness against Staphylococcus aureus, among other microorganisms, confirming its potential as an Ayurvedic treatment for bacterial infections.
4) Ayurveda (Ayus-veda):
Ayurveda is an ancient system of medicine from India that uses herbs and natural remedies. Vidangadi Churna is an Ayurvedic formulation, whose study aims to validate its therapeutic benefits and standardize its preparation according to modern pharmacognostic and phytochemical standards.
5) Chudasama:
Chudasama Hardik Y is one of the authors of the study on Vidangadi Churna. As a PhD scholar, he contributed to the research that explores the pharmacognostic, phytochemical, and antimicrobial properties of this traditional Ayurvedic medicine.
6) Medicine:
Medicine encompasses the science and practice of diagnosing, treating, and preventing disease. Vidangadi Churna, an Ayurvedic medicine, is studied for its potential application in treating infections caused by microorganisms like Klebsiella aerogenes and Escherichia coli.
7) India:
India is the origin of Ayurveda and the location where this study was conducted. The National Institute of Ayurveda in Jaipur, Rajasthan, India, facilitated the research on Vidangadi Churna to scientifically validate its traditional uses.
8) Discussion:
The discussion in the research paper examines the results of the study on Vidangadi Churna, including its antimicrobial properties and potential benefits. The researchers compare their findings with existing modern treatments, highlighting Ayurveda's potential in addressing microbial infections without severe side effects.
9) Triphala (Tri-phala):
Triphala is a traditional Ayurvedic herbal formulation composed of three fruits: Amalaki (Embilica officinalis), Vibhitaki (Terminalia Bellerica), and Haritaki (Terminalia chebula). Vidangadi Churna includes Triphala as one of its constituent components, contributing to its therapeutic properties.
10) Vidanga (Vidamga):
Vidanga, scientifically known as Embelia ribes, is a key ingredient in Vidangadi Churna. It is valued in Ayurveda for its medicinal properties, including antimicrobial and anthelmintic effects, and plays a significant role in the effectiveness of Vidangadi Churna.
11) Pippali (Pippalin):
Pippali, or Piper longum, is another constituent of Vidangadi Churna. It is known for its therapeutic properties in Ayurveda, such as digestive and antimicrobial benefits, which contribute to the overall efficacy of the Vidangadi Churna formulation.
12) Jaipur:
Jaipur is the city in Rajasthan, India, where the National Institute of Ayurveda is located. The research on Vidangadi Churna was conducted here, ensuring the study follows rigorous scientific methods within a reputed Ayurvedic academic institution.
13) Rasa (Rasha):
In Ayurveda, 'Rasa' refers to the taste of a substance or drug, which influences its therapeutic properties. Vidangadi Churna’s ingredients possess specific 'Rasa', contributing to its overall efficacy in treating various health conditions, as detailed in the study.
14) Embelia ribes:
Embelia ribes, commonly known as Vidanga, is an important herb in Ayurveda. It is included in Vidangadi Churna for its medicinal value, particularly for its antimicrobial and anthelmintic properties, which were highlighted in the research findings.
15) Rasashastra (Rasa-shastra, Rasasastra):
[see source text or glossary: Rasa-shastra]
16) Bhagandara (Bhagamdara):
In Ayurveda, Bhagandara refers to fistula-in-ano, a medical condition characterized by abnormal connections between the rectum and the skin. Vidangadi Churna is mentioned in Ayurvedic texts for its use in treating conditions like Bhagandara, indicating its historical therapeutic application.
17) Krimighna (Krmighna, Krimi-ghna):
Krimighna refers to a category of Ayurvedic treatments that are anthelmintic or anti-parasitic. Vidangadi Churna includes ingredients known for their Krimighna properties, making it effective against parasitic infections as confirmed by its antimicrobial activity in the study.
18) Vibhitaki:
Vibhitaki, scientifically known as Terminalia bellerica, is one of the three fruits in Triphala, an important constituent of Vidangadi Churna. It is recognized in Ayurveda for its therapeutic benefits, such as detoxifying and rejuvenating properties.
19) Rajasthan:
Rajasthan is a state in India where the National Institute of Ayurveda, Jaipur, is located. The study on Vidangadi Churna was conducted in this region, ensuring the research adheres to Ayurvedic practices and scientific validation within Indian academic standards.
20) Krimiroga (Krmiroga, Krimi-roga):
Krimiroga refers to diseases caused by parasitic worms or microbes in Ayurvedic medicine. The study on Vidangadi Churna assesses its effectiveness against pathogens responsible for Krimiroga, validating its traditional use for such infections.
21) Substance:
Substance in this context refers to the individual components or compounds within a medicinal formulation. Vidangadi Churna consists of various active substances like phenolic compounds and alkaloids, which contribute to its antimicrobial properties as identified in the study.
22) Haritaki:
Haritaki, scientifically known as Terminalia chebula, is one of the three fruits in the Triphala formulation. It is used in Vidangadi Churna and is valued in Ayurveda for its therapeutic effects, including digestive and detoxifying properties.
23) Prabhava:
Prabhava in Ayurveda refers to the unique or specific action of a drug or substance that cannot be explained by its Rasa (taste), Guna (quality), Veerya (potency), or Vipaka (post-digestion effect). Vidangadi Churna’s therapeutic efficacy includes both known and unique actions (Prabhava).
24) Rasayana (Rasa-ayana):
Rasayana refers to the Ayurvedic practice of rejuvenation or promoting longevity and vitality. The ingredients in Vidangadi Churna, such as Triphala, possess Rasayana properties, contributing to the formulation's overall health benefits beyond its antimicrobial effects.
25) Toxicity:
Toxicity refers to the degree to which a substance can cause harm to an organism. The study on Vidangadi Churna aims to validate its safety by ensuring it meets Ayurvedic pharmacopoeia standards and demonstrates minimal toxicity compared to modern antibiotics.
26) Shastra (Sastra):
[see source text or glossary: Shastra]
27) Amalaki:
Amalaki, or Embilica officinalis, is another essential fruit in the Triphala mixture. It is included in Vidangadi Churna for its extensive therapeutic properties, including antioxidant and anti-inflammatory effects, which support the formulation's efficacy.
28) Kalpana:
[see source text or glossary: Kalpana]
29) Disease:
Disease here refers to any condition that disrupts normal bodily functions. The study on Vidangadi Churna investigates its effectiveness in treating infections caused by various disease-causing microorganisms like Klebsiella aerogenes, demonstrating its potential as an Ayurvedic therapeutic option.
30) Kushtha (Kustha):
Kustha Roga refers to skin diseases in Ayurvedic terminology. Vidangadi Churna is documented in Ayurvedic texts like Yogratnakar as a treatment for Kustha Roga, and the study assesses its antimicrobial properties to support its usage in modern contexts.
31) Bitter:
Bitter is one of the tastes or Rasa according to Ayurveda and is associated with various therapeutic effects. The Vidangadi Churna has a bitter taste, which contributes to its anthelmintic and digestive properties, as indicated in the study's findings.
32) Kriya:
[see source text or glossary: Kriya]
33) Ayus (Ayush):
[see source text or glossary: Ayush]
34) Guna:
Guna in Ayurvedic terminology refers to the inherent qualities or attributes of a substance that contribute to its therapeutic effects. Vidangadi Churna’s efficacy in treating infections derives from the beneficial Guna of its ingredients like phenolic compounds, tannins, and alkaloids.
Other Science Concepts:
Discover the significance of concepts within the article: �Pharmacognostic, Phytochemical, and Antimicrobial Study of Vidangadi Churna�. Further sources in the context of Science might help you critically compare this page with similair documents:
Quality Control, Thin Layer Chromatography, Phytochemical study, Macroscopic study, Antimicrobial agent, Vidangadi Churna, Staphylococcus aureus, Pharmacognosy, Escherichia coli, Pseudomonas aeruginosa, Agar well diffusion method, Standardization of drug, Antimicrobial Study, Physiochemical study, Activity index, WHO guideline, Klebsiella aerogenes.