Study of draksha gritha for managing anemia in pregnancy.
Journal name: Ayushdhara
Original article title: A clinical study of draksha gritha in the management of anaemia in pregnancy (garbhini pandu)
AYUSHDHARA is an international peer-reviewed journal. It focuses on research in Ayurveda, Yoga, Unani, Siddha, Homeopathy, Allopathy, and Pharmaceutical Sciences.
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G Sri Harshitha
Assistant Professor, Dept.of Prasuti Tantra and Stree Roga, Sushruta Ayurvedic Medical College, Bangalore
Sunitha Joshi
Professor and HOD, P.G Unit of Prasuti Tantra and Stree Roga, Dr. B.R.K.R. G A C. Hyderabad
A. Sulochana
I/C Professor, P.G Unit of Prasuti Tantra and Stree Roga, Dr. B.R.K.R. G A C. Hyderabad
Yogitha Bali M.R
Professor and HOD, Dept of Shareera Rachana, Sushruta Ayurvedic Medical College, Bangalore
Divya Nagari N
Assistant Professor, Department of Samhita and Siddhanta, Sushruta Ayurvedic Medical College, Bangalore
Manisha Rajput
Assistant Professor, Department of Shalakya Tantra, Sushruta Ayurvedic Medical College, Bangalore
Ayushdhara:
(A peer-reviewed, bi-monthly open-access journal)
Full text available for: A clinical study of draksha gritha in the management of anaemia in pregnancy (garbhini pandu)
Year: 2020 | Doi: 10.47070/ayushdhara.v7i2.527
Copyright (license): CC BY-NC-SA 4.0
Download the PDF file of the original publication
Summary of article contents:
1) Introduction
Pregnancy is a critical period in a woman's life characterized by increased nutritional demands, particularly for iron, which is essential for both maternal health and fetal development. The Ayurvedic term "Pandu" refers to a condition akin to anemia, commonly observed in pregnant women, known as "Garbhini Pandu." This clinical study aimed to explore the efficacy of Draksha Gritha, a remedy mentioned in Ayurvedic texts, in the management of anemia during pregnancy. The study included 30 patients, administered Draksha Gritha twice daily on an empty stomach, for a duration of 90 days. Both subjective and objective parameters were assessed to evaluate treatment outcomes.
2) Efficacy of Draksha Gritha in Treating Anemia
The clinical trial highlighted the significance of Draksha Gritha in managing Garbhini Pandu, where a statistically significant improvement was observed across various symptoms. The initial mean hemoglobin (Hb) levels of the patients increased from an average of 8.473 gms% to 10.91 gms% post-treatment, demonstrating the effectiveness of the herbal preparation in enhancing hemoglobin concentration. Additionally, other subjective symptoms such as pallor, glossitis, and edema also showed marked improvement, indicating that the constituents of Draksha Gritha successfully addressed key manifestations of anemia in pregnancy.
3) Importance of Dietary Considerations
The study also examined dietary influences on anemia in pregnant women, noting that half of the participants consumed vegetarian diets, which are typically lower in bioavailable iron compared to non-vegetarian options. The findings indicated that patients with a non-vegetarian diet experienced better outcomes, attributed to the superior absorption of heme iron found in animal products. The results underscored the crucial role of nutritional intake during pregnancy, suggesting that dietary modifications may enhance treatment effectiveness when combined with Ayurvedic interventions, such as Draksha Gritha.
4) Conclusion
Overall, the clinical study confirmed Draksha Gritha as a safe and effective treatment for Garbhini Pandu, with statistically significant improvements in both subjective symptoms and objectively measured hemoglobin levels. The results advocate for the integration of Ayurvedic approaches in managing pregnancy-related anemia, emphasizing the importance of holistic care that includes dietary considerations alongside herbal remedies. This research highlights the potential of traditional knowledge in addressing contemporary health challenges faced by pregnant women, paving the way for further studies to validate and expand on these findings.
FAQ section (important questions/answers):
What is the aim of the clinical study on Draksha Gritha?
The study aimed to evaluate the effectiveness of Draksha Gritha in managing anaemia in pregnancy, known as Garbhini Pandu, by measuring changes in haemoglobin levels and other related symptoms.
What are the key findings related to Draksha Gritha's effectiveness?
Results showed significant improvements in pallor, glossitis, and haemoglobin levels among patients. Of the participants, 76% experienced excellent to good improvement in their symptoms after 90 days of treatment.
What demographic characteristics were noted among the study participants?
The majority of participants were aged 23-27 years, primarily housewives, and 63.33% followed a vegetarian diet. Most patients exhibited low haemoglobin levels, highlighting dietary influences on anaemia during pregnancy.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Study of draksha gritha for managing anemia in pregnancy.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Draksha (Draksa):
Draksha, which means grapes, are used in 'Draksha Ghrita' mentioned in Ayurveda. These grapes (Draksha) have multiple health benefits, especially in treating anemia, as they have 'Rakthaprasadana' and 'Jeevaniya' properties.
2) Ghrita (Ghrta):
'Ghrita' translates to ghee in Ayurveda. It has 'Vatapittahara' and 'Varnaprasadana' properties, making it beneficial for treating anemia (Pandu) in pregnant women (Garbhini).
3) Pandu (Pamdu, Pamde):
'Pandu' refers to pallor and is comparable to anemia in modern medicine. The study focuses on treating 'Garbhini Pandu', which refers to anemia during pregnancy.
4) Garbhini:
'Garbhini' denotes a pregnant woman. 'Garbhini Pandu' refers to anemia occurring during pregnancy, which was the focus of the study using 'Draksha Ghrita'.
5) Drug:
The term 'Drug' in this context refers to 'Draksha Ghrita', which was used to treat 'Garbhini Pandu' (anemia in pregnant women).
6) Disease:
'Disease' in this text often refers to anemia during pregnancy, known as 'Garbhini Pandu' in Ayurveda.
7) Bhrama:
'Bhrama' means giddiness, which is one of the subjective parameters assessed in the study on 'Garbhini Pandu'.
8) Tantra (Tamtra, Tantrism):
'Tantra' refers to the specialized branches of knowledge in Ayurveda, such as 'Prasuti Tantra' dealing with obstetrics and gynecology.
9) Dhatu:
'Dhatu' refers to the basic bodily tissues in Ayurveda. 'Rasa Dhatu' is one specific kind, whose improper function is linked to 'Garbhini Pandu'.
10) Roga:
'Roga' means disease in Sanskrit. 'Panduroga' is the term for anemia.
11) Rasa (Rasha):
In this context, 'Rasa' refers to the nutritive fluid considered essential in Ayurveda. 'Rasa Dhatu' deficiencies can lead to 'Garbhini Pandu'.
12) Pregnant:
A 'Pregnant' woman is referred to as 'Garbhini' in Ayurveda. The study focused on treating anemia in pregnant women using 'Draksha Ghrita'.
13) Prasuti:
�Prasuti Tantra� is the branch of Ayurveda that deals with obstetrics and gynecology, under which the study on 'Garbhini Pandu' was conducted.
14) Anupana:
'Anupana' refers to the vehicle used to administer a medicine. In this study, 'Sukoshnadugdha' (warm milk) was used as the 'Anupana' for 'Draksha Ghrita'.
15) Pitta:
'Pitta' is one of the three doshas in Ayurveda, associated with fire and metabolic processes. 'Draksha' has 'Pittashamaka' (Pitta-pacifying) properties.
16) Blood:
The improvement of Hemoglobin (Hb%) in 'Blood' was one of the objectives of treating 'Garbhini Pandu' with 'Draksha Ghrita'.
17) Diet:
'Diet' is crucial in Ayurveda; poor diet can cause or exacerbate 'Pandu Roga'. The study notes that non-vegetarian diets improved outcomes due to better iron absorption.
18) Ghi (Ghee):
'Ghee', referred to as 'Ghrita' in Ayurveda, is used in the preparation of 'Draksha Ghrita'. It has 'Vatapittahara' (balances Vata and Pitta) properties.
19) Rasadhatu (Rasa-dhatu):
'Rasa-dhatu' is the primary fluid tissue in Ayurveda, crucial for nourishment. Improper function of 'Rasa Dhatu' in mothers can lead to 'Garbhini Pandu'.
20) Panduroga (Pandu-roga, Pamduroga):
'Pandu-roga' is the Ayurvedic term for anemia. The study focuses on 'Garbhini Pandu', which refers specifically to anemia during pregnancy.
21) Karma (Karman):
'Karma' in this context refers to the therapeutic actions of a substance. 'Draksha' has 'Rakthaprasadana' (purifies blood) and other beneficial 'Karmas'.
22) Depression:
In the context of 'Edema', 'Depression' refers to the pitting observed in the skin. The study graded edema levels based on depression depth.
23) Medicine:
'Medicine' here refers to 'Draksha Ghrita', which was administered to pregnant women with anemia.
24) Edema (Oedema):
'Edema' refers to swelling, often assessed in the lower extremities. One of the objective parameters in the study for evaluating 'Garbhini Pandu'.
25) Food:
'Food' and nutrition play a significant role in managing 'Pandu Roga'. The study discusses the impact of diet on anemia.
26) Goghrita (Goghrta, Go-ghrita):
'Go-ghrita' is cow ghee. It was a key ingredient in 'Draksha Ghrita', used to treat 'Garbhini Pandu' due to its 'Vatapittahara' properties.
27) Substance:
'Substance' here refers to the ingredients in 'Draksha Ghrita', which have specific medicinal 'Karmas' or properties.
28) Ayurveda (Ayus-veda):
Ayurveda is the ancient Indian system of medicine under which 'Prasuti Tantra', 'Draksha Ghrita', and 'Garbhini Pandu' are studied and managed.
29) Shodhana (Sodhana):
'Shodhana' refers to detoxification treatments which are often avoided during pregnancy. Thus, 'Shamana' treatments were preferred for 'Garbhini Pandu'.
30) Kashyapa (Kasyapa, Kashya-pa, Kashyapanamdana):
Acharya 'Kashyapa' is an ancient Ayurvedic scholar who mentioned 'Garbhini Pandu' as a symptom related to pregnancy.
31) Parinama:
'Parinama' refers to the transformation processes in the body, such as the conversion of 'Rasa Dhatu' to 'Raktha Dhatu'.
32) Samhita:
'Samhita' refers to classical Ayurvedic texts. 'Draksha Ghrita' is mentioned in the Charaka 'Samhita'.
33) Nidana:
'Nidana' refers to the causative factors or etiology of a disease. Various 'Nidanas' for 'Pandu Roga' are food habits and lifestyle issues.
34) Kalka:
'Kalka' refers to a paste form of medicinal ingredients used in Ayurvedic preparations, such as 'Draksha Kalka' in 'Draksha Ghrita'.
35) Varna:
'Varna' refers to color. In the study, 'Panduta' of the skin is a primary symptom, indicating pale 'Varna' due to anemia.
36) Balya:
'Balya' in Ayurveda refers to strength-promoting properties. 'Draksha' has 'Balya' properties beneficial for pregnant women with anemia.
37) Birth:
'Birth' refers to the process or act of giving life. 'Garbhini Paricharya' in Ayurveda aims to ensure a healthy pregnancy and safe 'Birth'.
38) Fish:
'Fish' is mentioned as part of a non-vegetarian diet contributing to better iron absorption and improving anemia in 'Garbhini'.
39) Rheumatoid arthritis:
'Rheumatoid arthritis' is a systemic disease that can complicate pregnancy and was one of the exclusion criteria in the study.
40) Shalakyatantra (Salakyatantra, Shalakya-tantra, Shalakyatamtra):
'Shalakya-tantra' is the branch of Ayurveda dealing with diseases above the clavicle, referenced in the affiliations of the study authors.
41) Pharmacological:
The study refers to 'Pharmacological' activities of ingredients like Draksha, noting properties like anti-inflammatory and antihypertensive effects.
42) Rasavahasrotas (Rasavaha-srotas):
'Rasavahasrotas' are the channels that transport the nutritive fluids (Rasa) in the body, crucial in the context of 'Garbhini Pandu'.
43) Garbhasthapaka (Garbha-sthapaka):
'Garbhasthapaka' refers to substances that help sustain pregnancy. 'Draksha' has Garbhasthapaka properties, important for managing 'Garbhini Pandu'.
44) Transformation (Transform, Transforming):
'Transformation' refers to the process where 'Rasa Dhatu' converts to 'Raktha Dhatu', crucial for understanding anemia treatment in Ayurveda.
45) Ranjakapitta (Ranjaka-pitta):
'Ranjaka-pitta' is the sub-type of Pitta responsible for blood formation and coloring, significant in treating 'Pandu Roga'.
46) Sharirasthana (Sarirasthana, Sharira-sthana):
'Sharirasthana' is a section of the Charaka Samhita, where details about bodily structures and functions, as well as 'Garbhini Pandu', are explained.
47) Vatapittahara (Vatapitta-hara):
'Vatapittahara' properties are those that balance Vata and Pitta doshas, important in treating 'Pandu Roga' with 'Draksha Ghrita'.
48) Phytochemical:
'Phytochemical' refers to bioactive compounds in plants. Draksha has phytochemicals like dehydro ascorbic acid, beneficial for treating anemia.
49) Madhyamapaka:
'Madhyamapaka' refers to a moderate cooking method in Ayurveda used in preparing 'Draksha Ghrita' for better efficacy and absorption.
50) Malnutrition:
'Malnutrition' is a crucial factor leading to 'Pandu Roga'. Low socio-economic status and poor diet practices contribute significantly to anemia.
51) Inflammation:
'Inflammation' could be a symptom or condition treated with the anti-inflammatory properties of 'Draksha' in managing 'Garbhini Pandu'.
52) Vivarnatva:
'Vivarnatva' is a term denoting a lack of color or pallor, which can be related to anemia and is a part of 'Garbhini Pandu'.
53) Discussion:
'Discussion' usually follows the results in a research paper, elaborating on findings and their implications. Here, it discusses 'Garbhini Pandu' and 'Draksha Ghrita'.
54) Siddhanta (Siddha-anta, Siddhamta):
'Siddhanta' refers to fundamental principles. 'Samhita Siddhanta', or classical Ayurvedic texts, guide treatments like 'Draksha Ghrita' for 'Garbhini Pandu'.
55) Vibhitaki:
'Vibhitaki' is one of the ingredients in 'Ghrita Murchana', a process used in preparing 'Draksha Ghrita'.
56) Prasadana:
'Prasadana' properties bring tranquility. 'Draksha' and 'Ghrita' have 'Rakthaprasadana' and 'Varna prasadana' properties, helping with 'Garbhini Pandu'.
57) Vivarnata (Vivarna-ta):
'Vivarnata' denotes pallor or loss of color, a symptom of anemia closely related to 'Garbhini Pandu'.
58) Knowledge:
'Knowledge', especially about nutrition and health, was crucial for better treatment outcomes in 'Garbhini Pandu'.
59) Vibandha:
'Vibandha' means constipation, one of the symptoms treated by 'Draksha'.
60) Aushadha (Ausadha):
'Aushadha' means medicine. In this study, 'Draksha Ghrita' is the 'Aushadha' used for treating 'Garbhini Pandu'.
61) Haritaki:
'Haritaki' is one of the herbs used in 'Ghrita Murchana' for preparing 'Draksha Ghrita'.
62) Brimhana (Brmhana):
'Brimhana' refers to nourishing and building properties. 'Draksha' has 'Brimhana' properties, aiding in the treatment of 'Garbhini Pandu'.
63) Rasayana (Rasa-ayana):
'Rasayana' refers to rejuvenating therapies. 'Ghrita' holds 'Rasayana' properties, which contribute to overall health and longevity.
64) Krishata (Krsata):
'Krishata' means emaciation. 'Draksha' is used to combat such symptoms, making it beneficial for 'Garbhini Pandu'.
65) Hridrava (Hrdrava):
'Hrdrava' refers to palpitations, a symptom measured in the study on 'Garbhini Pandu'.
66) Swelling:
Swelling, specifically 'edema', was one of the objective parameters used to measure the effectiveness of the treatment for 'Garbhini Pandu'.
67) Murchana (Murcchana):
'Murchana' is a process in Ayurveda used in 'Ghrita' preparations. 'Ghrita Murchana' is done as part of preparing 'Draksha Ghrita'.
68) Shastra (Sastra):
'Shaastra' refers to classical texts in Ayurveda, which provide guidelines for treating conditions like 'Garbhini Pandu'.
69) Madhura:
'Madhura' is a sweet taste. 'Draksha' has a 'Madhura' rasa and is used for its nourishing properties, beneficial in treating 'Garbhini Pandu'.
70) Amalaki:
'Amalaki' is one of the herbs used in 'Ghrita Murchana', important for preparing 'Draksha Ghrita'.
71) Prastha (Prashtha):
'Prastha' is a measure denoting approximately 800 ml, used in the preparation of 'Ghrita' for Draksha Ghrita.
72) Ranjaka (Ramjaka):
'Ranjaka' refers to a sub-type of Pitta responsible for giving color to 'Raktha' (blood). Proper function is crucial to treating 'Pandu Roga'.
73) Snigdha:
'Snigdha' means oily or unctuous. 'Ghrita' (ghee) has snigdha properties, which help balance 'Vata' and 'Pitta' doshas.
74) Dusita (Dushita):
'Dushita' means vitiated. Improper function of 'Rasa Dhatu' results in 'Dushita' conditions leading to 'Garbhini Pandu'.
75) Haridra:
'Haridra' (turmeric) is one of the ingredients used in 'Ghrita Murchana' for preparing 'Draksha Ghrita'.
[Note: The above list is limited to 75. Total glossary definitions available: 107]
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