Anti-inflammatory effect of Chandrashura (Lepidium sativum Linn.) an experimental study
Journal name: AYU (Journal of Research in Ayurveda)
Original article title: Anti-inflammatory effect of Chandrashura (Lepidium sativum Linn.) an experimental study
AYU is an internationally recognized quarterly journal dedicated to advancing research in Ayurveda. The journal covers a wide range of topics, including clinical and pharmacological research in Ayurveda's eight branches, herbal remedies, phytochemistry, and ethnomedicine.
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Nita D. Raval
B. Ravishankar
B. K. Ashok
AYU (Journal of Research in Ayurveda):
(An International Quarterly Journal of Research in Ayurveda)
Full text available for: Anti-inflammatory effect of Chandrashura (Lepidium sativum Linn.) an experimental study
Year: 2013 | Doi: 10.4103/0974-8520.123132
Copyright (license): CC BY-NC-SA 4.0
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Summary of article contents:
Lepidium sativum Linn. (Chandrashura) of Family Cruciferae (Brassicaceae) is being used by the people of Gujarat for treating inflammatory condition like arthritis. To evaluate its anti-inflammatory activity, Charles Foster albino rats were selected and experiments were carried out in three groups, therapeutic dose group, twice of therapeutic dose group and control group. In Carrageenan-induced paw oedema, the test drug produced moderate anti-inflammatory activity; however, the effect did not show statistically significant activity due to variation in the data of the control group. In formaldehyde-induced paw oedema in rats, the test drug produced moderate to significant suppression. This indicates that Chandrashura has a strong inhibitory effect on proliferation of fibroblasts and also probably has connective tissue modulation effect. Keywords: Anti-Inflammatory, carrageenan and formaldehyde-induced paw oedema, Chandrashura (Lepidium sativum Linn.)
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Statistical analysis, Control group, Anti-inflammatory activity, Experimental model, Inflammatory condition, Institutional animal ethics committee, Lepidium sativum Linn, Double dose group, Carrageenan-induced paw edema, Formaldehyde-induced paw edema, Statistically significant level, Preliminary screening, In vitro and in vivo, Paw volume, Dose-dependent activity, Fibroblast proliferation, Observation and result.