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Study of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ and piracetam in amnesia

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Journal name: Ancient Science of Life
Original article title: Study of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ and piracetam in amnesia
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
This page presents a generated summary with additional references; See source (below) for actual content.

Original source:

This page is merely a summary which is automatically generated hence you should visit the source to read the original article which includes the author, publication date, notes and references.

Author:

Kapil Deo Yadav, K. R. C. Reddy, Vikas Kumar


Ancient Science of Life:

(A quarterly multi-disciplinary scientific research journal in Ayurveda)

Full text available for: Study of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ and piracetam in amnesia

Year: 2012

Copyright (license): CC BY-NC-SA


Summary of article contents:

Introduction

The study evaluated the effects of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, an Ayurvedic formulation, in comparison to the standard drug piracetam, on amnesia induced by scopolamine in Charles Foster rats. Aiming to explore potential treatments for cognitive disorders, the research highlights the significance of herbal remedies in mental health, referencing traditional knowledge from Ayurvedic texts. The formulation of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ combines several herbal ingredients known for their neuroprotective effects, and the study investigates their ability to reverse scopolamine-induced cognitive deficits.

Antiamnesic Effects of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹

The primary finding of the study was that both µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ and piracetam significantly antagonized the effects of scopolamine, demonstrating their potential as antiamnesic agents. Through various tests—such as the elevated plus maze, passive avoidance, and active avoidance tests—the researchers observed that treated rats showed improved memory retention and learning capabilities compared to control groups. Notably, there was no significant difference in the effectiveness of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ and piracetam, suggesting that µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ might act through mechanisms similar to those of cholinergic drugs, which are known to enhance cognitive function.

Conclusion

The study concludes that µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ is an effective herbal alternative for mitigating cognitive impairments related to amnesia, showing comparable efficacy to piracetam. This finding positions µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ as a valuable option in Ayurvedic medicine for addressing learning and memory disorders. The results encourage further exploration of traditional herbal formulations, underscoring their relevance in contemporary therapeutic contexts for mental health issues.

FAQ section (important questions/answers):

What was the objective of the study on µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹?

The objective was to compare the effects of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ with piracetam in treating amnesia induced by scopolamine in rats.

What methodology was used to evaluate antiamnesic activity?

Antiamnesic activity was evaluated through modified elevated plus maze, passive avoidance, and active avoidance tests after administering scopolamine and treatments to rats.

What were the results of treating rats with µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹?

Both dosages of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ significantly reversed scopolamine-induced amnesia, showing similar effectiveness to the standard drug, piracetam.

What conclusions were drawn from the study's findings?

The study concluded that both µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ and piracetam antagonized scopolamine's effects, indicating that µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ may be effective in treating learning and memory disorders.

Glossary definitions and references:

Scientific and Ayurvedic Glossary list for “Study of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ and piracetam in amnesiaâ€�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.

1) Brahmi:
[see source text or glossary: #µþ°ùÄå³ó³¾Ä«#] is an herb known for its potential cognitive benefits and its role in treating mental disorders, specifically as a key ingredient in µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, as it is derived from the plant Bacopa monnieri, which aligns with the principles of Ä€yurveda.

2) Ghrita (Ghrta):
[see source text or glossary: #Ghrita#] is the alternate Sanskrit term referring to medicinal Ghee, emphasizing its importance in the preparation of therapeutic formulations such as µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ for cognitive benefit.

3) Brahmighrita (Brahmighrta, Brahmi-ghrita):
[see source text or glossary: #µþ°ùÄå³ó³¾Ä«-ghá¹›ta#] is a specific formulation combining µþ°ùÄå³ó³¾Ä« with ³Ò³óá¹›t²¹, used to support cognitive functions and combat amnesia, demonstrating significant effectiveness against the impacts of scopolamine in scientific studies.

4) Drug:
[see source text or glossary: #Drug#] in the context of the study refers to substances like piracetam, which are used as references to evaluate the efficacy of herbal formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, especially in enhancing memory and combating amnesia.

5) Ghi (Ghee):
[see source text or glossary: #Ghee#] represents the traditional clarified butter used in Ä€yurvedic medicine, acting as a vehicle for various herbal treatments, including µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, and providing beneficial fats that support mental health.

6) Ayurveda (Ayus-veda):
[see source text or glossary: #Ayurveda#] is the holistic system of medicine that encompasses various treatments, including herbal formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, to promote mental health and well-being.

7) Science (Scientific):
[see source text or glossary: #Science#] in this context pertains to the methodical study of the effects of substances like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ and piracetam on mental disorders through rigorous experimentation and statistical analysis, bridging traditional practices with modern validation.

8) Mental disorder:
[see source text or glossary: #Mental disorder#] encompasses various conditions affecting cognitive functions, such as depression and anxiety, which studies like the one on µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ aim to treat and understand through both traditional Ä€yurvedic and modern scientific methods.

9) Activity:
[see source text or glossary: #Activity#] often refers to the behavioral or physiological processes affected by treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, specifically regarding how they influenced the learning and memory activities in experimental models of amnesia.

10) Rasashastra (Rasa-shastra, Rasasastra):
[see source text or glossary: #Rasa-shastra#] is a branch of Ä€yurveda focused on the study of metallic and herbal compounds, providing a scientific basis for the use of substances like µþ°ùÄå³ó³¾Ä« in treatments for mental health and cognitive enhancement.

11) Depression:
[see source text or glossary: #Depression#] is a common mental disorder addressed within Ä€yurveda, with herbal remedies including µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ utilized for their potential to improve mood and cognitive functions, alongside lifestyle modifications.

12) Shastra (Sastra):
[see source text or glossary: #Shastra#] means 'scripture' or 'treatise' in the context of Ä€yurveda, where it refers to the extensive knowledge system governing the use of substances like µþ°ùÄå³ó³¾Ä« in promoting mental health and wellness.

13) Anxiety:
[see source text or glossary: #Anxiety#] is another mental health condition that may be addressed via treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ according to Ä€yurveda, focusing on restoring balance through natural remedies and lifestyle alterations.

14) Kushtha (Kustha):
[see source text or glossary: #°­³Üṣṭ³ó²¹#] refers to a condition mentioned in Ä€yurveda, linked with mental disturbances and characteristics of various disorders, which can benefit from formulations involving herbs like µþ°ùÄå³ó³¾Ä«.

15) Kalka:
[see source text or glossary: #Kalka#] denotes a paste made from herbal components in Ä€yurvedic medicine, used in the preparation of formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, aiding in the therapeutic enhancement of mental health treatments.

16) Blood:
[see source text or glossary: #Blood#] is significant in Ä€yurvedic philosophy and science, as it plays a crucial role in the distribution of nutrients and medicinal substances in the body, including those from herbal formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹.

17) Rasa (Rasha):
[see source text or glossary: #Rasa#] refers to 'taste' and is also linked to the essence and medicinal properties of substances in Āyurveda, particularly in relation to their effects on mental health when included in treatments.

18) Vaca:
[see source text or glossary: #³Õ²¹³¦Äå#] is a significant herb (Acorus calamus) used in formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ for its cognitive-enhancing properties, particularly beneficial in addressing cognitive impairments.

19) Shankhapushpi (Sankhapuspi, Samkhapuspi):
[see source text or glossary: #Åš²¹á¹…k³ó²¹±è³Üá¹£pÄ«#] is another herb included in µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, recognized for its role in supporting mental clarity and functions in the context of Ä€yurvedic treatments for memory and learning.

20) Training:
[see source text or glossary: #Training#] in the study context refers to the behavioral conditioning process for the rats used to evaluate memory and learning, illustrating how treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ can impact these activities.

21) Water:
[see source text or glossary: #Water#] is fundamental for all living beings and plays an essential role in delivering nutrients and medicines within the body, including the fluid formulations in Āyurveda.

22) Acorus calamus:
[see source text or glossary: #Acorus calamus#] is the scientific name for the herb ³Õ²¹³¦Äå, used in µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ for its potential benefits in enhancing cognitive functions and combating mental disorders.

23) Puranaghrita (Puranaghrta, Purana-ghrita):
[see source text or glossary: #±Ê³Ü°ùÄåṇa-²µ³óá¹›t²¹#] refers to aged or traditionally prepared ghee, often regarded as more potent in medicinal properties and used in the preparation of formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹.

24) Murchana (Murcchana):
[see source text or glossary: #²ÑÅ«°ù³¦³¦³ó²¹²ÔÄå#] is a specific preparatory process in Ä€yurveda used to enhance the efficacy of ³Ò³óá¹›t²¹, which can impact the quality and effectiveness of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ in treating mental disorders.

25) Medicine:
[see source text or glossary: #Medicine#] encompasses all remedies, including herbal preparations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, that are utilized within Ä€yurveda to improve health, particularly in the realm of mental health.

26) Dravya:
[see source text or glossary: #Dravya#] refers to substances used in Ä€yurveda, including the herbs and compounds found in µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, vital for their therapeutic properties in addressing mental health.

27) Purana:
[see source text or glossary: #±Ê³Ü°ùÄåṇa#] denotes the aged aspect of substances, particularly Ghee, in Ä€yurveda that often enhances its medicinal effectiveness in treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹.

28) Vikara:
[see source text or glossary: #³Õ¾±°ìÄå°ù²¹#] indicates 'disorder or disturbance' in Sanskrit, directly relating to mental disorders that formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ are designed to alleviate according to Ä€yurvedic principles.

29) Unmada:
[see source text or glossary: #±«²Ô³¾Äå»å²¹#] refers to insanity or severe mental disturbance in Ä€yurvedic terms, which treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ can potentially address through their cognitive-enhancing properties.

30) Medhya:
[see source text or glossary: #Medhya#] describes substances in Ä€yurveda that promote intellect and memory, a quality attributed to the ingredients of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ used to enhance cognitive function.

31) Shukra (Sukra):
[see source text or glossary: #Åš³Ü°ì°ù²¹#] denotes bodily essence or reproductive tissue in Ä€yurvedic medicine, which can be influenced by certain herbal formulations, potentially linking to overall mental health.

32) Diet:
[see source text or glossary: #Diet#] signifies the importance of nutritional intake within Ä€yurveda, impacting both physical and mental health, and is an integral part of treatment protocols including those with µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹.

33) Zingiber officinale:
[see source text or glossary: #Zingiber officinale#] is ginger, recognized within Āyurveda for its various health benefits, often used in the dietary context to promote overall wellness including mental clarity.

34) Mental health:
[see source text or glossary: #Mental health#] encapsulates emotional and psychological well-being, directly addressed by treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ aimed at supporting cognitive functions and alleviating disorders.

35) Shukradhatu (Sukradhatu, Shukra-dhatu):
[see source text or glossary: #Åš³Ü°ì°ù²¹-dhÄtu#] is a term that relates to reproductive tissue in Ä€yurvedic medicine, which can be affected by the quality of herbs used in formulations targeting mental disorders.

36) Nagakesara (Nagakeshara, Naga-kesara):
[see source text or glossary: #±·Äå²µ²¹°ì±ð²õ²¹°ù²¹#] corresponds to a flower used in certain Ä€yurvedic preparations, contributing to the potential therapeutic effects of formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ in mental health treatment.

37) Perception:
[see source text or glossary: #Perception#] in the context of mental health relates to the cognitive processes affected by treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, which aims to enhance clarity of thought and understanding.

38) Discussion:
[see source text or glossary: #Discussion#] in research papers includes analyzing the findings from studies involving µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, showcasing its effects on mental disorders and exploring traditional medicine's relevance in contemporary science.

39) Vibhitaki:
[see source text or glossary: #³Õ¾±²ú³óÄ«³Ù²¹°ìÄ«#] is a component known in Ä€yurveda for its medicinal properties, potentially contributing to the effectiveness of formulations aimed at enhancing cognitive functions like those in µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹.

40) Matulunga (Matulumga, Matulamga):
[see source text or glossary: #²ÑÄå³Ù³Ü±ô³Üá¹…g²¹#] is a type of fruit used in traditional medicine; when applied in formulations, it helps improve overall mental and physical health, pertinent to the preparation of µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹.

41) Murcchita:
[see source text or glossary: #²ÑÅ«°ù³¦³¦³ó¾±³Ù²¹#] describes the process of preparing medicated Ghee like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, establishing its potency and efficacy in treating cognitive impairments and supporting mental health.

42) Substance:
[see source text or glossary: #Substance#] refers to any material used in treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, highlighting the importance of active ingredients that affect mental health outcomes.

43) Apasmara:
[see source text or glossary: #´¡±è²¹²õ³¾Äå°ù²¹#] signifies epilepsy in Ä€yurvedic literature, emphasizing the need for effective treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ aimed at stabilizing mental health and cognitive clarity.

44) Haritaki:
[see source text or glossary: #±á²¹°ùÄ«³Ù²¹°ìÄ«#] refers to a well-known herb in Ä€yurveda used for its health benefits, contributing to formulations including µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ which aim to enhance cognitive functions.

45) Vagbhata:
[see source text or glossary: #³ÕÄå²µ²ú³ó²¹á¹­a#] is one of the ancient Ä€yurvedic scholars, whose texts outline the principles of using substances like µþ°ùÄå³ó³¾Ä« in mental health treatments, further scientific understanding of their applications.

46) Aushadhi (Ausadhi, Aushadhin, Ausadhin):
[see source text or glossary: #Aushadhi#] refers to medicinal herbs in Ä€yurveda, which are crucial in preparing formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ intended for cognitive enhancement and treatment of mental disorders.

47) Epilepsy:
[see source text or glossary: #Epilepsy#] is a neurological disorder addressed within Ä€yurveda using formulations such as µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ to help regulate brain function and reduce symptoms related to cognitive impairment.

48) Amalaki:
[see source text or glossary: #Ä€³¾²¹±ô²¹°ìÄ«#] is an Ayurvedic herb used in the preparation of various medicines; it plays a role in enhancing the effects of formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ on mental clarity and wellness.

49) Svarasa (Sva-rasa):
[see source text or glossary: #Svarasa#] translates to juice or essence, crucial in the preparation of herbal medicines like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, which focus on delivering active ingredients effectively for mental health benefits.

50) Kaphaja:
[see source text or glossary: #Kaphaja#] refers to a type of disorder influenced by the Kapha dosha in Ä€yurveda, which may be treated with formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ aimed at restoring balance and improving mental health.

51) Brahman:
[see source text or glossary: #Brahman#] is associated with ultimate consciousness in Ä€yurvedic philosophy, symbolizing the high spiritual aim of formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, which seek to enhance overall mental well-being.

52) Haridra:
[see source text or glossary: #±á²¹°ù¾±»å°ùÄå#] signifies turmeric in Ä€yurveda, which can enhance µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹'s properties, showcasing a blend of herbs aimed at enhancing mental clarity and wellness.

53) Channel:
[see source text or glossary: #Channel#] relates to the pathways in the body through which nutrients and medicines travel, crucial in understanding how substances like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ affect mental health conditions.

54) Quality:
[see source text or glossary: #Quality#] refers to the effectiveness and properties of formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, emphasizing the importance of high-quality ingredients in achieving therapeutic aims in mental health.

55) Mantra (Mamtra):
[see source text or glossary: #Mantra#] are sacred chants in Ä€yurveda, sometimes combined with treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ to enhance the healing process and promote better mental health through spiritual resonance.

56) Caraka:
[see source text or glossary: #Caraka#] is one of the foundational figures in Ä€yurveda, whose teachings guide the use of remedies like µþ°ùÄå³ó³¾Ä« for treating mental health conditions and enhancing cognitive functions.

57) Skandha (Skamdha, Skamda):
[see source text or glossary: #Skanda#] relates to specific conditions or entities within Ayurvedic texts, connecting to treatments such as µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ that seek to address cognitive imbalances.

58) Bitter:
[see source text or glossary: #Bitter#] is a taste associated with many herbs used in Ä€yurveda that can stimulate digestive and cognitive functions, relevant to the properties of ingredients in µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹.

59) Reason:
[see source text or glossary: #Reason#] underlines the rationale for selecting particular herbs and formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ for mental health treatments, grounded in both traditional knowledge and scientific evidence.

60) Pitta:
[see source text or glossary: #Pitta#] denotes one of the three doshas in Ä€yurveda, influencing mental and physical health, where treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ may address imbalances contributing to mental disorders.

61) Sneha:
[see source text or glossary: #Sneha#] signifies the concept of unctuousness in Ä€yurveda, crucial to understanding how formulations like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ are absorbed and utilized to treat mental health effectively.

62) Varti (Vartin):
[see source text or glossary: #Varti#] refers to the wick-like shape characteristic of Ghee preparations in Ä€yurveda, emphasizing the unique texture and form of medicinal Ghee like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ which aims to treat mental health issues.

63) Nasya (Nashya):
[see source text or glossary: #Nasya#] is a method of administration in Ä€yurveda, involving the nasal application of substances like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹, utilized for direct effects on cognitive functions and overall mental wellness.

64) Dhatu:
[see source text or glossary: #¶Ù³óÄå³Ù³Ü#] refers to the bodily tissues in Ä€yurveda, signifying the importance of nourishing all bodily systems, including those influencing mental health, through the use of restorative herbs like those in µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹.

65) Vata:
[see source text or glossary: #³ÕÄå³Ù²¹#] is the dosha associated with movement and metabolism, which can contribute to various mental disorders; treatments like µþ°ùÄå³ó³¾Ä« ³Ò³óá¹›t²¹ can help to balance this dosha to promote mental wellness.

Other Science Concepts:

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Discover the significance of concepts within the article: �Study of Brahmi Ghrta and piracetam in amnesia�. Further sources in the context of Science might help you critically compare this page with similair documents:

Brahmighrita, Medicated ghee, Central nervous system, Institutional Animal Ethical committee, Bacopa monnieri, Passive avoidance test, Learning and memory activity, Active avoidance test, Elevated plus maze test, Lipid Soluble Drugs, Scopolamine-induced amnesia, Snehapaka process, Institute of Medical Sciences, Antiamnesic activity, Psychotropic drug, Manasa vikara, Calmodulin.

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