Antibacterial Activity of Coldenia Procumbens Linn
Journal name: Ancient Science of Life
Original article title: Antibacterial Activity of Coldenia Procumbens Linn
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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Mrs. AP. Beena
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Antibacterial Activity of Coldenia Procumbens Linn
Year: 2005
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
Coldenia procumbens Linn, a prevalent weed in India, is recognized for its diverse medicinal applications in traditional Indian systems of medicine such as Ayurveda and Siddha. Despite its common usage, there is limited literature on its pharmacological effects, prompting a preliminary study to explore its antibacterial properties. The research is particularly relevant given the rising issue of antibiotic resistance in treating superficial wounds, which are often resistant to standard treatments and plagued by drug-resistant microorganisms.
Antibacterial Properties of Coldenia Procumbens Linn
The study investigated the antibacterial activity of the aqueous extract of Coldenia procumbens Linn against various bacterial strains, including both Gram-positive and Gram-negative bacteria. Utilizing the Kirby-Bauer antimicrobial susceptibility test, the zones of inhibition were measured and compared with the standard antibiotic ciprofloxacin. The results demonstrated that while Coldenia procumbens exhibited antibacterial activity, it was less potent than the standard drug. Notably, the extract was effective against organisms such as Bacillus subtilis and Staphylococcus aureus, indicating the presence of bioactive chemical constituents that support its traditional use in treating infections.
Conclusion
The findings of this preliminary study affirm the potential of Coldenia procumbens Linn as an alternative to synthetic antibiotics, particularly in the context of traditional medicine. Despite its lower antibacterial activity compared to ciprofloxacin, the plant demonstrates a noteworthy ability to inhibit bacterial growth, underscoring its relevance in herbal medicine. Future research focused on isolating and purifying the active components of this plant could further validate its therapeutic efficacy and possibly lead to the development of new antibacterial agents derived from natural sources.
FAQ section (important questions/answers):
What is Coldenia procumbens Linn and its uses?
Coldenia procumbens Linn, known as 'Tripunkhi' in Hindi, is a herb with various medicinal applications, including treatment for abscesses, leucorrhoea, menorrhagia, and rheumatism.
What was the purpose of the study on Coldenia procumbens?
The study aimed to investigate the antibacterial activity of Coldenia procumbens, as it is commonly used in traditional medicine but lacks sufficient scientific literature on its pharmacological effects.
Which microorganisms were tested in the antibacterial study?
The study tested various gram-positive and gram-negative bacteria, including Bacillus subtilis, Staphylococcus aureus, E. coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae.
How was the antibacterial activity of the plant measured?
The Kirby-Bauer antimicrobial susceptibility test was used to evaluate the zone of inhibition of the aqueous extract of Coldenia procumbens compared to ciprofloxacin.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Antibacterial Activity of Coldenia Procumbens Linn�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Antibiotic (Antibacterial):
'Antibiotic' pertains to substances that can destroy or inhibit the growth of bacteria. Coldenia procumbens Linn's assessment against established antibiotics illustrates its potential usefulness in treating infections, particularly as resistance to conventional antibiotics increases. This emphasizes the importance of exploring plants with antibacterial qualities in modern medicine.
2) Activity:
In this context, 'Activity' refers to the antibacterial properties exhibited by Coldenia procumbens Linn. The study measured these activities against various bacterial strains through zones of inhibition. Understanding the activity of this weed helps justify its use in folk medicine and encourages further exploration of its therapeutic potentials.
3) Drug:
'Drug' denotes a substance used to diagnose, cure, or prevent disease. In the study, ciprofloxacin serves as the standard drug for comparison. The investigation assesses Coldenia procumbens Linn in relation to this synthetic option, highlighting the ongoing search for effective, natural alternatives in medical therapies.
4) Medicine:
'Medicine' refers to the field concerned with the diagnosis, treatment, and prevention of disease. Coldenia procumbens Linn has traditional applications in systems such as Ayurveda and Sidha, showcasing the integration of ancient knowledge with contemporary research, contributing to a broader understanding of medicinal plants.
5) Science (Scientific):
The term 'Science' encompasses systematic study and experimentation to understand natural phenomena. The rigorous methodology used to evaluate the antibacterial properties of Coldenia procumbens Linn illustrates how scientific inquiry can validate traditional knowledge and lead to new discoveries in pharmacology.
6) Pharmacological:
'Pharmacological' relates to the actions and effects of drugs. The study of Coldenia procumbens Linn's antibacterial activity contributes to the pharmacological understanding of plant-derived substances, indicating a potential therapeutic role. This can guide future experimental and clinical research in developing safe and effective treatments.
7) Chemotherapy:
'Chemotherapy' is primarily associated with the treatment of cancer using chemical substances. However, in a broader context, it refers to any treatment with drugs aimed at combating diseases. The resistance developed by bacteria against common chemotherapeutic agents underscores the search for alternative treatments, such as those derived from plants.
8) Discussion:
'Discussion' encompasses the analysis of findings in research. Within the study of Coldenia procumbens Linn, the discussion evaluates its antibacterial effects, comparing them to standard treatments, and suggests pathways for further research. This critical dialogue is vital for understanding the implications of results in medicinal chemistry.
9) Ayurveda (Ä€yurveda, Ayus-veda):
'Ayurveda' is an ancient Indian system of medicine advocating a holistic approach to health. Coldenia procumbens Linn is utilized in this framework for various ailments. The research adds scientific validation to Ayurvedic practices, demonstrating that traditional medicine can complement and enhance modern medical therapies with natural remedies.
10) Allergy:
'Allergy' refers to the immune response to typically harmless substances, potentially resulting in adverse reactions. The mention of allergies in the context of antibiotics highlights a significant issue in conventional medicine. Natural alternatives, like Coldenia procumbens Linn, may provide treatment options with fewer allergic reactions or side effects.
11) Water:
'Water' is the solvent used in the extraction process to evaluate Coldenia procumbens Linn's antibacterial properties. The choice of water as a medium not only aligns with traditional practices but also highlights the environmental friendliness and accessibility of the extraction methods used for therapeutic potential exploration.
12) Ulcer:
'Ulcer' denotes damaged tissue resulting from infection or irritation, often requiring antibacterial treatment. The study's focus on Coldenia procumbens Linn suggests its traditional application in treating such wounds, underscoring the need to explore plant-based options for effective, safer wound care solutions.
13) Cita:
'Sidha' refers to a traditional system of medicine similar to Ayurveda, prevalent in South India. Coldenia procumbens Linn’s usage in Sidha highlights its cultural significance and establishes a bridge between traditional practices and modern scientific research, emphasizing the importance of incorporating historical knowledge into contemporary healthcare.
Other Science Concepts:
Discover the significance of concepts within the article: �Antibacterial Activity of Coldenia Procumbens Linn�. Further sources in the context of Science might help you critically compare this page with similair documents:
Indian systems of medicine, Antibacterial activity, Zone of inhibition, Traditional systems of medicine, Gram positive bacteria, Adverse side effects, Chemical constituent, Ciprofloxacin, Medicinal application, Superficial wound, Coldenia procumbens Linn.