Comparison of eugenia jambolana bark extracts' MICs on diarrhea pathogens.
Journal name: Ancient Science of Life
Original article title: Comparison of minimum inhibitory concentration of water soluble extracts of eugenia jambolana lam. (fam. myrtaceae) barks of different ages on dysentery and diarrhoea forming micro � organisms
The ANSCI is a peer-reviewed, open-access journal focused on Ayurveda and traditional medicines. It publishes original research, reviews, and literary studies linking traditional knowledge with modern science, covering disciplines like botany, ethnomedicine, pharmacology, and clinical research.
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Original source:
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Asis Prosun Maiti, Subodh Chandra Pal, Debaprasad Chattopadhyay, Samar De, Anutosh Nandy
Ancient Science of Life:
(A quarterly multi-disciplinary scientific research journal in Ayurveda)
Full text available for: Comparison of minimum inhibitory concentration of water soluble extracts of eugenia jambolana lam. (fam. myrtaceae) barks of different ages on dysentery and diarrhoea forming micro � organisms
Year: 1985
Copyright (license): CC BY-NC-SA
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Summary of article contents:
Introduction
This study examines the antibacterial effects of water-soluble extracts from the barks of Eugenia jambolana Lam., a plant belonging to the Myrtaceae family, specifically focusing on the barks of two different ages: five years and ten years. The research aimed to determine the Minimum Inhibitory Concentration (MIC) of these extracts against various microorganisms that cause dysentery and diarrhea, including Salmonella viballerup and several strains of Shigella. Notably, previous Ayurvedic literature has cited the antidysentery and antidiarrheal properties of Eugenia jambolana, making this investigation timely and relevant.
Antibacterial Effectiveness of Young versus Older Barks
The findings revealed a significant difference in antibacterial activity depending on the age of the bark. The water-soluble extract from the barks of five-year-old plants exhibited a stronger inhibitory effect against microorganisms such as Salmonella viballerup, Shigella dysenteriae 10, and Shigella boydii 5, showing inhibitory effects starting from concentrations as low as 800 µg/ml. Conversely, the bark from ten-year-old plants displayed better efficacy against Shigella dysenteriae 2, indicating that both extracts possess varying potencies against specific pathogens. The results suggest that the age of the bark plays a crucial role in its antibacterial properties, which can inform future herbal medicine applications and phytochemical studies.
Conclusion
In conclusion, this preliminary investigation underscores the importance of examining the age of plant materials in relation to their medicinal efficacy. The antibacterial effects of Eugenia jambolana vary with the age of its bark, with younger barks exhibiting superior inhibition against a broader range of dysentery and diarrhea-causing microorganisms. These findings support the traditional uses of this plant in Ayurvedic medicine and highlight the potential for further research into the therapeutic applications of Eugenia jambolana extracts in treating bacterial infections. Future studies could focus on isolating specific bioactive compounds and establishing a clearer understanding of the mechanisms behind their antibacterial properties.
FAQ section (important questions/answers):
What was the purpose of the study on Eugenia jambolana barks?
The study aimed to investigate the antibacterial activity of water soluble extracts from five and ten-year-old barks of Eugenia jambolana against dysentery and diarrhoea-causing microorganisms.
What method was used to determine Minimum Inhibitory Concentration?
The Minimum Inhibitory Concentration (MIC) method was employed to evaluate the antibacterial activity, measuring the concentration at which microbial growth is effectively inhibited.
Which microorganisms were tested in this research?
The study tested various microorganisms including Salmonella viballerup, Shigella dysenteriae, Shigella boydii, and Vibrio cholerae, assessing their growth in response to barks' extracts.
What were the findings regarding the age of the barks?
Younger barks (five years old) showed better inhibitory effects on certain microorganisms, while older barks (ten years old) exhibited effectiveness against specific strains of Shigella dysenteriae.
Glossary definitions and references:
Scientific and Ayurvedic Glossary list for “Comparison of eugenia jambolana bark extracts' MICs on diarrhea pathogens.�. This list explains important keywords that occur in this article and links it to the glossary for a better understanding of that concept in the context of Ayurveda and other topics.
1) Drug:
In the context of the study, 'Drug' refers to the water-soluble extracts derived from the bark of Eugenia jambolana, which are investigated for their effectiveness against specific pathogenic microorganisms. The results of the Minimum Inhibitory Concentration (MIC) tests help in understanding the pharmacological potential of these extracts as therapeutic agents.
2) Water:
'Water' signifies the solvent used to extract active compounds from the Eugenia jambolana bark. The focus on water-soluble extracts indicates the relevance of such compounds in herbal medicine and their possible applications in treating dysentery and diarrhea, enhancing public health through potential antibacterial properties.
3) Antibiotic (Antibacterial):
'Antibacterial' highlights the purpose of the research, which is to determine the effectiveness of Eugenia jambolana extracts against harmful bacteria causing dysentery and diarrhea. Understanding the antibacterial activity is critical for developing natural remedies and may offer alternatives to conventional antibiotics in combating resistant microbial strains.
4) Activity:
'Activity' reflects the biological function of the compounds extracted from Eugenia jambolana bark, specifically their capacity to inhibit or kill microorganisms. The study assesses how effective these extracts are at various concentrations, contributing to knowledge of their potential medicinal use in treating infections.
5) Discussion:
'Discussion' represents the section of the research where authors interpret and analyze the findings. In this part, they explore the implications of their results, the observed efficacy of the extracts, compare with previous literature, and provide insights on practical applications, along with directions for future research.
6) Science (Scientific):
'Science' embodies the systematic approach taken in the study to explore the medicinal properties of Eugenia jambolana bark. It emphasizes the importance of empirical evidence, rigorous experimentation, and methodical analysis in validating traditional claims about herbal medicine and contributes to the body of scientific knowledge on natural products.
Other Science Concepts:
Discover the significance of concepts within the article: �Comparison of eugenia jambolana bark extracts' MICs on diarrhea pathogens.�. Further sources in the context of Science might help you critically compare this page with similair documents:
Control, Jadavpur University, Antibacterial activity, Minimum inhibitory concentration, Ethanolic extract, Water soluble extract, Shigella dysenteriae, Petroleum ether, Dysentery and Diarrhoea, Incubator, Dried powdered, Vibrio cholerae, Micro organism.