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Significance of Sham group

The Sham group, according to Science, is a control group in experiments that receives a non-active treatment, such as 10% fructose feeding, to account for dietary influences. This group does not undergo any noise exposure or receive NAC treatment, establishing a baseline for comparison. Additionally, the Sham group consists of rats that have undergone an operation without specific interventions like bile duct ligation, which helps researchers evaluate any impacts from the surgical procedure itself.

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The concept of Sham group in scientific sources