Significance of Plasmid DNA
Plasmid DNA refers to double-stranded, circular DNA constructs that exist independently of chromosomal DNA, primarily found in bacteria. They can carry therapeutic genes and are widely utilized in gene therapy, DNA vaccines, and genetic engineering. Plasmid DNA plays a crucial role in research and biotechnology, facilitating the delivery of genes for proteins and antibiotic resistance. Its analysis helps in understanding genetic properties and assessing the impact of various substances, such as nanoparticles, on DNA structure and stability.
Synonyms: Circular dna, Recombinant dna, Plasmid vector, Extrachromosomal dna, Cloning vector
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The concept of Plasmid DNA in scientific sources
Plasmid DNA consists of circular, extrachromosomal DNA molecules that are crucial in genetic engineering and biotechnology, particularly for gene delivery and analyzing genetic properties, such as those in Bacillus thuringiensis.
From: The Malaysian Journal of Medical Sciences
(1) This is the genetic material found in the isolates, which can carry genes for antibiotic resistance, and the analysis of its presence and size was conducted.[1] (2) This refers to the genetic material, that is taken up by host cells and subsequently expresses the antigen of interest.[2]