Significance of Nitric oxide
Nitric oxide (NO) is a gaseous signaling molecule that plays a crucial role in various physiological processes, including immune response and regulation of blood flow. It is produced from L-arginine and functions as a potent vasodilator, helping to lower blood pressure. While essential for maintaining vascular health, excessive levels of nitric oxide can lead to cellular injury and contribute to diseases such as diabetes and periodontal disease. It is also involved in neuroprotection and inflammatory responses in the central nervous system.
Synonyms: No
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The concept of Nitric oxide in scientific sources
Nitric oxide, a diffusible gas produced in the nasal cavity, is crucial for enhancing mucociliary motion and functioning as a host defense mechanism, highlighting its importance in respiratory health and immune response.
From: The Malaysian Journal of Medical Sciences
(1) This mediates host resistance to infectious microorganisms and has antiparasitic and anti-adhesion effects, and is a potent inhibitor of TNF production.[1] (2) This is a radical that is scavenged by the methanol extract of C. asiatica, along with DPPH and reducing power, and the methanolic extract has concentration-dependent activity.[2] (3) NAC negatively modulates the production of this in endotoxin-treated rats, playing a critical role in neurite outgrowth of neuroblastoma cells.[3] (4) This is a molecule that is studied in relation to its involvement in the rostral ventromedial medulla, and it is studied in the context of modulating pain signals.[4] (5) Nitric oxide is a molecule whose production can be increased in human monocytes when stimulated by Mycobacterium tuberculosis DNA, as well as when cells are induced by mediators.[5]