Significance of Nasal delivery
Nasal delivery is a method for drug absorption through the nasal cavity, providing several benefits such as bypassing the blood-brain barrier and avoiding first-pass metabolism in the liver. This approach utilizes the nasal mucosa's large surface area and high vascularity, allowing drugs to reach systemic circulation or target the central nervous system. Additionally, microemulsions can enhance drug absorption by improving stability and solubility. Nasal delivery can also include traditional practices like the use of Anu Tailam for specific health conditions.
Synonyms: Nasal administration, Intranasal delivery, Nasal route, Nasal absorption, Nasal application, Intranasal administration, Nasal spray
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The concept of Nasal delivery in scientific sources
Nasal delivery is a drug administration method that utilizes the nasal mucosa for absorption, employing microemulsions to improve stability and solubility, enabling direct access to the brain by bypassing the blood-brain barrier.
From: World Journal of Pharmaceutical Research
(1) The process of administering drugs through the nasal cavity for local, systemic, or central nervous system effects.[1] (2) The administration of drugs through the nasal route for either local or systemic effects.[2] (3) A drug delivery method that utilizes the nasal cavity due to its large surface area, high vascularity, and ability to bypass first-pass metabolism in the liver.[3] (4) The method of delivering drugs through the nasal mucosa for systemic circulation.[4] (5) The method of delivering drugs through the nasal mucosa, with microemulsions enhancing the absorption of drugs by providing stability and solubility.[5]
From: Journal of Ayurveda and Integrative Medicine
(1) A method of administration described in the use of Anu Tailam, aimed at treating conditions affecting the upper body.[6]