Significance of Mutation
Mutation is defined as a change in the DNA sequence of a gene, which can lead to various outcomes that influence gene function and health. This alteration in the genetic material can affect the organism’s traits and may have implications for health, potentially causing diseases or contributing to diversity in traits. Understanding mutations is crucial in fields like genetics and medicine, as they play a significant role in evolution and individual development.
Synonyms: Modification, Alteration, Change, Variation, Transformation, Adjustment, Deviation, Adaptation, Evolution
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The concept of Mutation in scientific sources
Mutation involves changes in a gene's DNA sequence, leading to diverse effects on gene function and health, which can result in varying biological outcomes. It plays a crucial role in evolution and genetic diversity.
From: The Malaysian Journal of Medical Sciences
(1) This is an alteration in the genetic material, such as the p53 gene, which can lead to dysfunction.[1] (2) These are changes in the genetic material of a cell, and mutations in mtDNA contribute to some well characterized diseases; mtDNA is also implicated in several diseases and malignancies with poorly elucidated aetiologies.[2] (3) A change in the DNA sequence of a cell, which can lead to altered cell function.[3] (4) These are mutations that can be identified from the data from the EMR coupled with gene sequencing.[4] (5) This is a change in the DNA sequence, like the Filipino β°-deletion, that can lead to altered gene function and cause diseases like beta-thalassemia.[5]