Significance of Molecular characterization
Molecular characterization is the process of identifying and analyzing microorganisms at the molecular level, primarily using techniques such as DNA sequencing and amplification. This approach enables the identification of bacterial strains based on their genetic composition, which includes determining resistance mechanisms and studying the epidemiological aspects of various pathogens. Techniques like 16S rDNA analysis and PCR are essential in confirming species identity and understanding the characteristics and pathogenic potential of these microorganisms.
Synonyms: Molecular analysis, Molecular identification, Genetic analysis, Genetic characterization
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The concept of Molecular characterization in scientific sources
Molecular characterization involves identifying molecular structures and characteristics of substances, such as using RAPD markers for Cissus repanda and Jasmine species, to analyze genetic variation and confirm species identity.
From: The Malaysian Journal of Medical Sciences
(1) This involves examining the genetic makeup of a sample to identify and describe the specific genes, mutations, or other molecular features present in the sample.[1] (2) The process of analyzing the molecular structure and genetic mutations of organisms, particularly drug-resistant tuberculosis isolates in this context.[2] (3) The analysis of genetic variations and mutations to determine their implications in diseases, particularly in relation to β-thalassaemia.[3] (4) The process of studying the genetic basis of hemoglobin disorders to understand variations among different populations.[4] (5) The detailed analysis at a molecular level, often used to study genes and their functions related to specific disorders.[5]