Significance of Micronuclei
Micronuclei are small nuclei that occur when chromosomes or their fragments are not incorporated into daughter nuclei during cell division. They serve as indicators of genotoxic effects, such as those caused by deltamethrin and radiation exposure. These structures may be used as biological markers for chromosomal damage, highlighting the potential genotoxic impact of various agents. Their presence points to disruptions in normal cell division processes and underscores the importance of monitoring genotoxicity in various scientific contexts.
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The concept of Micronuclei in scientific sources
Micronuclei are small, nucleus-like structures formed in cells due to chromosomal disruption, serving as biological markers for genotoxicity. They indicate chromosomal damage and arise from improper segregation during cell division.
From: The Malaysian Journal of Medical Sciences
(1) These are small nuclei that form in cells, and are the origin of extrachromosomal elements, and are associated with blast cells in acute myeloid leukemia, and are indicators of genomic instability.[1] (2) Small nuclei that form as a result of chromosomal fragmentation; their presence can indicate radiation exposure effects.[2]