Significance of Loperamide
Loperamide is an antidiarrheal medication widely recognized for its effectiveness in reducing diarrhea by slowing gut movement. In various studies, it serves as a standard drug for comparison against the antidiarrheal properties of various plant extracts such as Clitorea ternatea, Dalbergia sissoo, Blumea lacera, and Mimosa pudica. By acting as a positive control, Loperamide helps evaluate the efficacy of these natural alternatives in treating diarrhea.
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The concept of Loperamide in scientific sources
Loperamide is utilized as a standard reference drug in studies comparing the antidiarrheal effectiveness of Blumea lacera and Clitorea ternatea extract, serving as a benchmark for evaluating their therapeutic benefits.
From: World Journal of Pharmaceutical Research
(1) A standard medication used to compare the antidiarrhoeal effects of Mimosa pudica in the study.[1] (2) An antidiarrheal medication that acts by slowing the movement in the gut, used as a standard in the study to compare the efficacy of the plant extract.[2] (3) A standard drug used in the study as a comparison for evaluating the antidiarrhoeal properties of various extracts of Dalbergia sissoo.[3] (4) A standard antidiarrheal drug used as a positive control in the study to compare the efficacy of plant extracts.[4] (5) Loperamide is a standard drug used as a comparison in this study to evaluate the antidiarrheal effectiveness of Blumea lacera.[5]
From: AYU (Journal of Research in Ayurveda)
(1) A standard drug used as a reference in the study to compare the effectiveness of Clitorea ternatea extract in reducing diarrhea.[6]