Significance of Kidney damage
Kidney damage is a serious condition characterized by impairment of kidney structure and function, leading to long-term complications. It can result from various factors, including untreated urinary tract infections, uncontrolled hypertension, exposure to toxins, and systemic diseases like diabetes and lupus. Indicators of kidney damage include elevated levels of creatinine, urea, and abnormalities in glomerular filtration rate. This damage can initiate inflammatory responses, fibrosis, and potentially progress to chronic kidney disease or end-stage renal disease if left untreated.
Synonyms: Renal impairment, Kidney injury, Renal damage, Nephropathy, Renal dysfunction, Renal injury, Kidney dysfunction.
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The concept of Kidney damage in scientific sources
Kidney damage involves impaired kidney function, often linked to systemic diseases like SLE, leading to issues such as proteinuria. It can manifest as structural or functional abnormalities, exacerbated by uncontrolled hypertension.
From: The Malaysian Journal of Medical Sciences
(1) Kidney damage, resulting from the UUO procedure, initiates a repair response that can lead to the restoration of a normal epithelium or maladaptive epithelium, possibly resulting in fibrosis.[1] (2) This is a factor that defines chronic kidney disease, and it can result from either pathological abnormalities or markers of damage, or an estimated glomerular filtration rate less than 60 mL/min/1.73 m 2 for more than three months.[2] (3) A general term for any type of harm or injury to the kidney, which can trigger various inflammatory and fibrotic processes.[3] (4) This is damage that is found to be exacerbated by the increase in BMI in diabetic patients, leading to CKD, and it is a health factor.[4] (5) This is the impairment of kidney structure and function, which can be detected using markers such as creatinine and cystatin C.[5]