Significance of Intrinsic pathway
The intrinsic pathway refers to a pathway of apoptosis activated by internal cellular signals, particularly related to mitochondrial function. It also encompasses a route for blood coagulation that is reliant on components found within the vascular system. This pathway includes various biological mechanisms, such as the response to DNA damage or lack of growth factors. Additionally, it involves elements of the coagulation cascade that are activated through traumatic contact and is influenced by factors like venom proteases.
Synonyms: Internal process
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The concept of Intrinsic pathway in scientific sources
The Intrinsic pathway is a blood coagulation route initiated by internal vascular elements. It activates through traumatic contact, involving factors present in blood and playing a critical role in the coagulation cascade.
From: The Malaysian Journal of Medical Sciences
(1) This is a cellular process involving caspase-9, and it is a key element in cell apoptosis, where the activation of caspase-9 is a critical step.[1] (2) Internal biological pathways within organisms that regulate various functions, including regeneration.[2]