Significance of IgG and IgM
IgG and IgM refer to specific antibodies that play a crucial role in immune response, particularly in COVID-19 testing. They are measured in ELISA tests to determine if there has been an immune response to the virus, with IgG indicating past infection and IgM signaling acute infection. Additionally, these antibodies are essential in therapeutic contexts, where IVIG enhances bactericidal activity by neutralizing and opsonizing IgG and IgM, aiding in phagocytosis. They are also markers for infections like hepatitis E.
Synonyms: Immunoglobulin g, Immunoglobulin m, Antibodies, Serum antibodies, Protective antibodies
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The concept of IgG and IgM in scientific sources
IgG and IgM are antibodies measured in blood tests; IgM signifies acute infection while IgG indicates past infections. They serve as markers for detecting hepatitis E virus presence in serum.
From: The Malaysian Journal of Medical Sciences
(1) These are two types of antibodies produced by the immune system in response to infection, playing a crucial role in the immune response.[1] (2) IVIG's beneficial mechanisms involve the improvement in serum bactericidal activity through the neutralisation and opsonisation of IgG and IgM antibodies, and the activation of phagocytosis.[2] (3) IgG and IgM are antibodies detected in ELISA tests for COVID-19, and their levels are measured to determine the presence of an immune response to the virus.[3] (4) Types of antibodies that are measured in blood tests; IgG indicates past infection or carrier state, while IgM indicates acute infection.[4]