Significance of Glibenclamide
Glibenclamide is a widely studied oral antihyperglycemic agent used in the management of type 2 diabetes, recognized for its capability to stimulate insulin secretion from the pancreas. It serves as a standard comparison in various studies assessing the efficacy of different polyherbal extracts and other agents aimed at reducing blood glucose levels. Additionally, its thrombolytic effects and docking scores make it a key reference drug in research focused on antidiabetic effects, enhancing its importance in diabetes management.
Synonyms: Glyburide, Insulin secretagogue, Oral hypoglycemic agent
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The concept of Glibenclamide in scientific sources
Glibenclamide is an antidiabetic drug utilized as a reference standard in studies, particularly for comparing its efficacy in managing blood sugar levels with other treatments like Saptarangyadi Ghanavati.
From: The Malaysian Journal of Medical Sciences
(1) This medication might ameliorate oxidative stress in the kidneys of diabetic rats to a certain extent, and administration of this and metformin, and repaglinide exhibited a significant reduction in MDA concentration.[1] (2) A standard diabetic drug used in the study that improved body weight and hormonal levels in diabetic mice.[2] (3) A reference drug used in the study to compare the hypoglycaemic effects of Persea americana extracts.[3]