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Significance of Folin–Ciocalteu reagent

Folin–Ciocalteu reagent is a versatile chemical reagent primarily utilized for determining the total phenolic content in plant extracts and assessing antioxidant activity. It operates through colorimetric assays, allowing measurement via spectrophotometry, often forming a blue colored chromogen in the presence of phenolic compounds or reducing agents. This reagent is essential in assessing polyphenols in various samples, including pharmaceuticals, and is commonly referenced in scientific studies aiming to quantify phenolic content relative to gallic acid.

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The concept of Folin–Ciocalteu reagent in scientific sources