Significance of Fibroblast cells
Fibroblast cells are critical components in various biological functions and are utilized in cytotoxicity tests, showing mild toxic effects from certain extracts. They are abundant in skin tissue, significantly contributing to wound healing by disrupting fibrin clots and producing extracellular matrix components. Additionally, fibroblast cells play an essential role in maintaining healthy gingiva and surrounding tissues, serving as a focus in studies evaluating the effects of Anbarnesa. Their multifunctional nature underscores their importance in tissue health and repair.
Synonyms: Fibroblast-like cells, Mesenchymal cells, Stromal cells
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The concept of Fibroblast cells in scientific sources
Fibroblast cells are abundant in skin tissue, crucial for wound healing by breaking down fibrin clots and generating extracellular matrix components. They also maintain healthy gingiva and surrounding tissues, evaluated in the context of Anbarnesa effects.
From: The Malaysian Journal of Medical Sciences
(1) Fibroblast cells are also part of the cellular processes driving kidney fibrosis, and their proliferation contributes to the excessive accumulation of extracellular matrix in the kidneys.[1] (2) These are cells that have been studied to determine the expression of certain genes and proteins in the context of drug-induced programmed cell death.[2] (3) Fibroblast cells are one of the normal cell lines used in the cytotoxicity test, and the extracts were found to have mild toxic effects on these cells.[3]