Significance of Diagnostic biomarker
A diagnostic biomarker is a biological marker that indicates the presence or progression of a disease, aiding in diagnosis and management. Examples include IL-21 levels, microRNAs, and ROS in colorectal cancer, as well as sFlt-1 and placental growth factor for pre-eclampsia. Additionally, biomarkers can predict tumor behavior in head and neck squamous cell carcinoma (HNSCC) and indicate the severity of periodontal diseases through molecules like ceruloplasmin and miR-223, facilitating personalized treatment options.
Synonyms: Biomarker, Diagnostic indicator, Biological marker, Clinical marker, Indicator, Marker, Sign
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The concept of Diagnostic biomarker in scientific sources
Diagnostic biomarkers are biological molecules, like miR-223 and IL-21, that indicate the presence or progression of diseases such as periodontal disease, aiding in their diagnosis and management.
From: The Malaysian Journal of Medical Sciences
(1) These are potential roles of microRNAs and ROS in colorectal cancer, and also therapeutic targets, as shown by the text.[1]