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Significance of Cytochrome c

Cytochrome c is a mitochondrial protein that plays a critical role in the apoptotic pathway. It is released from mitochondria during ischemia/reperfusion (I/R) injury, leading to the activation of caspases, which trigger apoptosis in cells such as HCT116 and HT-29. Its release signals the up-regulation of apoptotic processes, and it functions within the electron transport chain. Overall, cytochrome c is central to the mechanisms of programmed cell death.

Synonyms: Cytochrome c oxidase

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The concept of Cytochrome c in scientific sources

Science Books

Cytochrome c is a crucial protein residing in the mitochondrial intermembrane space, playing a dual role in apoptosis by activating caspases and functioning within the electron transport chain, with its release triggering cell death.

Significance in Scientific journals, articles, etc.:

From: The Malaysian Journal of Medical Sciences

(1) An increase in detectable levels of this was observed, which suggests the up-regulation of the apoptotic pathway in HCT116 and HT-29 cells, according to the text.[1]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.