Significance of Cross-over study
A cross-over study is a clinical trial design where participants receive multiple interventions sequentially, allowing for direct outcome comparisons within the same subjects. This design enables participants to experience both treatment and control conditions at different times. By alternating between different interventions, such as caffeinated and decaffeinated products, the study effectively measures outcomes, like pH, across various products. This unique structure facilitates a comprehensive evaluation of the effects of different treatments on the same group of participants.
Synonyms: Cross-over trial, Cross-over design, Crossover study, Crossover trial, Crossover design
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The concept of Cross-over study in scientific sources
A Cross-over study is a clinical trial design where participants receive multiple interventions sequentially, allowing for direct comparison of outcomes between treatments within the same subjects, enhancing the reliability of the results.
From: The Malaysian Journal of Medical Sciences
(1) This is a study design where participants experience all treatments (CHO, PLA, CON) in different sequences, and then the results are compared.[1]