Significance of Cowhage
Cowhage, scientifically known as Mucuna pruriens, is a plant recognized for its significant role as a non-histaminergic pruritogen. When injected into the skin, it induces intense itching without triggering the histamine response typically associated with allergic reactions. This unique property makes cowhage an important subject of study in understanding itching mechanisms and potential treatments for pruritus.
Synonyms: Velvet bean, Mucuna pruriens, Kapikachhu
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The concept of Cowhage in scientific sources
Cowhage, identified as Mucuna pruriens, is a plant recognized for its ability to induce severe itching without histamine involvement, making it a classical example of a non-histaminergic pruritogen when injected into the skin.
From: The Malaysian Journal of Medical Sciences
(1) A plant (Mucuna pruriens) known as a classic non-histaminergic pruritogen, causing intense itching when injected into the skin.[1]