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Significance of Controlled drug release

Controlled drug release is a sophisticated drug delivery method allowing for the gradual release of medication over a specified time. It ensures therapeutic effects are sustained while minimizing side effects by regulating the release rate from the drug's carrier system. This technique utilizes various formulations, such as polymers and nanoparticles, to achieve a predictable rate of drug release, thus maintaining effective drug concentrations and improving bioavailability. Overall, controlled drug release optimizes therapeutic outcomes, enhancing efficacy and reducing toxicity.

Synonyms: Regulated drug delivery, Targeted drug release, Sustained drug release, Sustained release, Extended release, Timed release, Prolonged release, Delayed release

The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.

The concept of Controlled drug release in scientific sources

Science Books

Controlled drug release involves the formulation of medications that release therapeutic agents at a predetermined rate. This method ensures prolonged pharmacological effects, often through the use of polymers, over a specified duration.

Significance in Scientific journals, articles, etc.:

From: World Journal of Pharmaceutical Research

(1) A mechanism by which the release of a drug from a delivery system is managed to achieve optimal therapeutic effects and minimize side effects.[1] (2) A delivery mechanism that modulates the release of a drug, ensuring that it occurs at a steady rate.[2] (3) A delivery mechanism that allows for the gradual release of a drug over time to maintain its therapeutic effect.[3] (4) A system with mechanisms that regulate the release rate of a drug over time, influenced by polymer choice and formulation design.[4] (5) The regulated release of a drug from its delivery system at a predetermined rate.[5]

From: Journal of Indian Society of Periodontology

(1) A drug delivery system designed to release a specific amount of medication over a specified timeframe.[6]

This section includes scientific research in the field of healthcare, often involving traditional medicine systems such as Ayurveda, Unani, Siddha and Holistic health. It includes papers from scientific journals classified as either original, clinical or experimental research, review articles or case reports.