Significance of Complete Freund's adjuvant
Complete Freund's adjuvant is an immunological agent used extensively in experimental models to induce arthritis, particularly in rats and mice. It involves injection of a mixture of mycobacterium and oil to simulate inflammatory conditions similar to rheumatoid arthritis. This allows researchers to evaluate the anti-inflammatory effects of various treatments, facilitating studies on chronic pain and inflammatory responses. Overall, it serves as a crucial method for understanding arthritis and assessing potential anti-arthritic therapies.
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The concept of Complete Freund's adjuvant in scientific sources
Complete Freund's adjuvant is utilized in experimental models to induce arthritis, enabling research into anti-arthritic treatments, and it mimics conditions akin to rheumatoid arthritis for better understanding and therapeutic development.
From: World Journal of Pharmaceutical Research
(1) A substance used to induce arthritis in experimental models, allowing researchers to study inflammatory responses and potential treatments.[1] (2) A method used to induce arthritis in animal models that involves injecting a mixture of mycobacterium and oil into the paw.[2] (3) An immunological agent used in experimental arthritis models to induce inflammation in the joints of rats.[3] (4) A substance used in experimental models to induce inflammatory pain in mice, creating a condition that mimics chronic pain.[4] (5) An experimental model used to induce arthritis in laboratory animals, serving as a close approximation to human rheumatoid arthritis.[5]
From: Journal of Ayurveda and Integrative Medicine
(1) A substance used to induce rheumatoid arthritis in experimental animals by causing an immune response.[6] (2) A substance used in this study to induce chronic arthritis for evaluating the anti-inflammatory effects of the pastes.[7] (3) A substance used to induce arthritis in the test subjects by injection to evaluate the effectiveness of Costus speciosus.[8]
From: AYU (Journal of Research in Ayurveda)
(1) A substance used to induce arthritis in experimental models, allowing the study of anti-arthritic treatments.[9] (2) A substance used to induce arthritis in experimental models, simulating conditions similar to rheumatoid arthritis.[10]