Significance of Comminution
Comminution is the scientific process involved in breaking down granules or pellets into smaller particle sizes, which is essential for tablet formulation. This technique is significant in the pharmaceutical industry as it helps achieve the desired consistency and uniformity in tablet composition, ultimately impacting the effectiveness of the medication. Proper comminution ensures that the active ingredients are well-distributed and readily available for absorption in the body.
Synonyms: Crushing, Grinding, Milling, Pulverization, Fragmentation
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The concept of Comminution in scientific sources
Comminution is the process of reducing granules or pellets into smaller particles, crucial for tablet formulation. This step enhances the consistency and effectiveness of pharmaceuticals, ensuring optimal performance in medication delivery.
From: World Journal of Pharmaceutical Research
(1) The process of breaking down the granules or pellets into smaller particle sizes for tablet formulation.[1]