Significance of Chemical interaction
Chemical interaction refers to the reactions that occur between drugs and excipients, potentially leading to the formation of new molecules and affecting drug stability and efficacy. These interactions are crucial in various processes, such as the blending of materials like chitosan and PVP, which can influence drug release and absorption. Understanding these interactions is essential for ensuring the stability and performance of pharmaceutical formulations, as they can affect properties like drug efficacy and safety through mechanisms such as hydrolysis and oxidation.
Synonyms: Chemical reaction, Chemical bonding, Chemical process, Molecular interaction
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The concept of Chemical interaction in scientific sources
Chemical interaction involves the interplay between a drug and its excipients, significantly influencing the drug's release and absorption. This relationship is crucial for optimizing drug formulations and ensuring effective therapeutic outcomes.
From: World Journal of Pharmaceutical Research
(1) The potential reactivity between a drug and its carrier, which in this study showed no significant evidence, indicating stability.[1] (2) The interplay between a drug and its excipients during formulation that could affect the drug's properties, such as stability and dissolution.[2] (3) The ways in which different chemicals influence each other's properties and behaviors.[3] (4) The interaction between the drug and the polymer that can enhance drug release properties, such as altering the swelling behavior of the polymer.[4] (5) The interaction between different chemical entities, affecting the properties and performance of nanoparticles.[5]