Significance of Cell-mediated immunity
Cell-mediated immunity is a crucial aspect of the immune system characterized by the direct involvement of T-cells in defending the body against intracellular pathogens and cancer cells. Unlike antibody-mediated responses, it relies on the activation of immune cells such as T-lymphocytes and cytokines to combat infections. This type of immunity is vital for targeting and destroying infected or abnormal cells, demonstrating its effectiveness in various infectious diseases and tumor immunity. It plays a significant role in maintaining overall immune health.
Synonyms: T-cell immunity, Cellular immunity, Adaptive immunity
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The concept of Cell-mediated immunity in scientific sources
Cell-mediated immunity is an immune response characterized by T-lymphocyte activation, focusing on immune cell involvement rather than antibodies. This protection against pathogens is assessed through various experimental models within the study.
From: The Malaysian Journal of Medical Sciences
(1) A type of immune response, and the presentation of a cryptococcoma is rarer when this is intact.[1] (2) An immune response that does not involve antibodies but is mediated by T cells and other immune cells.[2] (3) An immune response that does not involve antibodies but instead relies on the activation of phagocytes and T cells to eliminate infected cells.[3] (4) A type of immune response that is involved in the clearance of the malaria parasite during infection.[4] (5) An immune response that involves the activation of T cells and is primarily effective against intracellular pathogens like M. tuberculosis.[5]