Significance of Cell cycle arrest
Cell cycle arrest is the process by which cell division is halted, playing a crucial role in cancer treatment. It can occur in response to various factors such as DNA damage, stress, or therapeutic agents, effectively preventing the proliferation of damaged or cancerous cells. Various compounds, including ciprofloxacin and selenium, can induce cell cycle arrest, providing a strategy to slow down or stop cancer cell growth and potentially allow for cell repair or programmed death.
Synonyms: Growth arrest, Mitotic arrest, Cell proliferation inhibition, Quiescence
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Cell cycle arrest in scientific sources
Cell cycle arrest is a state where cells stop dividing, triggered by factors like inhibited kinases. This process halts cell division, enabling repair or apoptosis, particularly noted in hepatocellular carcinoma cell lines with specific treatments.
From: The Malaysian Journal of Medical Sciences
(1) This refers to the halt or slowing down of the progression of the cell cycle, which can occur in response to cellular stress or DNA damage.[1] (2) This refers to the stopping of the cell cycle, and the text mentions that certain compounds induce cell cycle arrest in human prostate carcinoma cells.[2] (3) The process of stopping the cell cycle, preventing cells from dividing, which can be utilized in cancer treatment.[3] (4) A halted state in the cell cycle induced by certain bacterial toxins that can lead to cell death and serve a pathogenic role.[4] (5) A mechanism through which andrographolide inhibits cancer cell growth by stopping the cell cycle progression.[5]