Significance of Cell cycle
The cell cycle is the organized series of phases that a cell navigates to duplicate its DNA and divide into two daughter cells. It comprises distinct stages, including G1, S, G2, and M phases, crucial for understanding cellular growth and division. Disruptions in the cell cycle can contribute to diseases like cancer, as this process is tightly regulated by proteins such as CDKs and cyclins. Consequently, targeting the cell cycle is a common strategy in cancer therapies to prevent uncontrolled cell proliferation.
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The concept of Cell cycle in scientific sources
The cell cycle is a regulated process comprising phases (G1, S, G2, M) crucial for genome duplication and cell division, impacted by proteins like CDKs and cyclins, with telomere shortening influencing chromosomal stability.
From: The Malaysian Journal of Medical Sciences
(1) This is a series of events that take place in a cell leading to its division and duplication of its DNA, and PTEN may control cell cycle.[1] (2) Cell cycle analysis was performed to evaluate the possibility of cell growth arrest, and the data revealed that cells were arrested in specific phases after treatment with a particular preparation of Zamzam water.[2] (3) TNP-470 showed a wide variety of antitumor activities by arresting this that prevents endothelial cells from entering the G1 phase, resulting in a decreased proliferation.[3] (4) This term refers to the series of events that take place in a cell leading to its division and duplication of its DNA to create two daughter cells.[4] (5) In proliferating cells, intoxication happens by altering cell morphology, by arresting this at the G2 phase to inhibit the cell growth and cell death by activating apoptotic cascade.[5]